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Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

http://www.wikidata.org/entity/Q34280083

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Gram-positive bacterial superantigen outside-in signaling causes toxic shock syndrome The staphylococcal enterotoxin (SE) family: SEB and siblings The potential use of toxin antibodies as a strategy for controlling acute Staphylococcus aureus infections.Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology.Vaccination against Staphylococcus aureus pneumonia A novel core genome-encoded superantigen contributes to lethality of community-associated MRSA necrotizing pneumonia.Levels of alpha-toxin correlate with distinct phenotypic response profiles of blood mononuclear cells and with agr background of community-associated Staphylococcus aureus isolates.Superantigens subvert the neutrophil response to promote abscess formation and enhance Staphylococcus aureus survival in vivo Humanized staphylococcal enterotoxin B (SEB)-specific monoclonal antibodies protect from SEB intoxication and Staphylococcus aureus infections alone or as adjunctive therapy with vancomycin Staphylococcal and streptococcal superantigen exotoxins In vitro and in vivo models of Staphylococcus aureus endophthalmitis implicate specific nutrients in ocular infection CD1d-independent activation of invariant natural killer T cells by staphylococcal enterotoxin B through major histocompatibility complex class II/T cell receptor interaction results in acute lung injury Novel antimicrobial peptides that inhibit gram positive bacterial exotoxin synthesis.Chronic superantigen exposure induces systemic inflammation, elevated bloodstream endotoxin, and abnormal glucose tolerance in rabbits: possible role in diabetes.Role of miRNA in the regulation of inflammatory genes in staphylococcal enterotoxin B-induced acute inflammatory lung injury and mortality Genotypic and phenotypic analysis of clinical isolates of Staphylococcus aureus revealed production patterns and hemolytic potentials unlinked to gene profiles and source.Novel Tissue Level Effects of the Staphylococcus aureus Enterotoxin Gene Cluster Are Essential for Infective Endocarditis.Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection.Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome Immunity to Staphylococcus aureus secreted proteins protects rabbits from serious illnesses.Comparison of Staphylococcus aureus strains for ability to cause infective endocarditis and lethal sepsis in rabbits Recurrent infections and immune evasion strategies of Staphylococcus aureus.Engineering a soluble high-affinity receptor domain that neutralizes staphylococcal enterotoxin C in rabbit models of disease Staphylococcal Enterotoxin B-specific monoclonal antibody 20B1 successfully treats diverse Staphylococcus aureus infections.Bacterial Toxins-Staphylococcal Enterotoxin B.Soluble T cell receptor Vβ domains engineered for high-affinity binding to staphylococcal or streptococcal superantigens Animal Models Used to Study Superantigen-Mediated Diseases.FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights.Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.Rabbit Model for Superantigen-Mediated Lethal Pulmonary Disease.Treatment with the hyaluronic acid synthesis inhibitor 4-methylumbelliferone suppresses SEB-induced lung inflammation.Therapeutic blockade of CD54 attenuates pulmonary barrier damage in T cell-induced acute lung injury.Concentration-dependent effects of antimicrobials on Staphylococcus aureus toxin-mediated cytokine production from peripheral blood mononuclear cells.Manipulation of Innate and Adaptive Immunity by Staphylococcal Superantigens.Live attenuated Salmonella typhimurium vaccines delivering SaEsxA and SaEsxB via type III secretion system confer protection against Staphylococcus aureus infection.

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P2860

Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

http://www.wikidata.org/entity/Q34280083

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

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Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

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Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

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type

label

Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

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Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

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Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

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Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

@ast

Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

@en

Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

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P1433

The Journal of Infectious Diseases

P1476

Staphylococcal superantigens cause lethal pulmonary disease in rabbits.

@en

P2093

David M Kranz

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Jessica H Rotschafer

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Kristi L Strandberg

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Rebecca A Buonpane

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Sara M Vetter

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P2860

Exotoxins of Staphylococcus aureus

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC

Staphylococcus aureus infections

Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia

Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease?

Invasive methicillin-resistant Staphylococcus aureus infections in the United States

Comparative analysis of lipopolysaccharide-induced tumor necrosis factor alpha activity in serum and lethality in mice and rabbits pretreated with the staphylococcal superantigen toxic shock syndrome toxin 1.

Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis.

The structural basis of T cell activation by superantigens.

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1690-1697

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11

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47565458

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2974057

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