Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts - Wikidata - wikimedia - TriplyDB

Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts

Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts

http://www.wikidata.org/entity/Q34280104

about

An integrated signal transduction network of macrophage migration inhibitory factor Does it make sense to target one tumor cell chemotactic factor or its receptor when several chemotactic axes are involved in metastasis of the same cancer?Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives Macrophage migration inhibitory factor involvement in breast cancer (Review)MIF Promotes Classical Activation and Conversion of Inflammatory Ly6C(high) Monocytes into TipDCs during Murine Toxoplasmosis.Concise Review: CXCR4/CXCL12 Signaling in Immature Hematopoiesis--Lessons From Pharmacological and Genetic Models Involvement of macrophage migration inhibitory factor and its receptor (CD74) in human breast cancer.Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors.CXCR7/CXCL12 axis is involved in lymph node and liver metastasis of gastric carcinoma.The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation.Tumor microenvironment macrophage inhibitory factor directs the accumulation of interleukin-17-producing tumor-infiltrating lymphocytes and predicts favorable survival in nasopharyngeal carcinoma patients.Cystic fibrosis sputum DNA has NETosis characteristics and neutrophil extracellular trap release is regulated by macrophage migration-inhibitory factor Bioactive lipids, LPC and LPA, are novel prometastatic factors and their tissue levels increase in response to radio/chemotherapy MIF, a controversial cytokine: a review of structural features, challenges, and opportunities for drug development.Stromal-dependent tumor promotion by MIF family members.Pathogenic roles of macrophage migration inhibitory factor during dengue virus infection.Human rhabdomyosarcoma cells express functional erythropoietin receptor: Potential therapeutic implications.25 Years On: A Retrospective on Migration Inhibitory Factor in Tumor Angiogenesis.Negative regulation of AMP-activated protein kinase (AMPK) activity by macrophage migration inhibitory factor (MIF) family members in non-small cell lung carcinomas Macrophage migration inhibitory factor has a permissive role in concanavalin A-induced cell death of human hepatoma cells through autophagy Human rhabdomyosarcoma cells express functional pituitary and gonadal sex hormone receptors: Therapeutic implications.The expressions of MIF and CXCR4 protein in tumor microenvironment are adverse prognostic factors in patients with esophageal squamous cell carcinoma.Arrest Functions of the MIF Ligand/Receptor Axes in Atherogenesis.CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia.Tumor-associated fibroblasts promote the proliferation and decrease the doxorubicin sensitivity of liposarcoma cells.Role of MIF/CD74 signaling pathway in the development of pleural mesothelioma Bioactive lipids S1P and C1P are prometastatic factors in human rhabdomyosarcoma, and their tissue levels increase in response to radio/chemotherapy A novel perspective on stem cell homing and mobilization: review on bioactive lipids as potent chemoattractants and cationic peptides as underappreciated modulators of responsiveness to SDF-1 gradients.Inflammation: what role in pediatric cancer?Beta cell function: the role of macrophage migration inhibitory factor.MIF Is Necessary for Late-Stage Melanoma Patient MDSC Immune Suppression and Differentiation.Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients.Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential.New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.Control of tumor-associated macrophage alternative activation by macrophage migration inhibitory factor.Macrophage migration inhibitory factor (MIF) is induced by cytotoxic drugs and is involved in immune escape and migration in childhood rhabdomyosarcoma.Macrophage migration inhibitory factor (MIF) expression in human malignant gliomas contributes to immune escape and tumour progression.Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology.Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion.The relevance of the migration inhibitory factor (MIF) for peripheral tissue response in murine sublethal systemic Aspergillus fumigatus infection.

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P2860

Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts

http://www.wikidata.org/entity/Q34280104

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Macrophage migration inhibitor ...... cancer-associated fibroblasts

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Macrophage migration inhibitor ...... cancer-associated fibroblasts

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Macrophage migration inhibitor ...... cancer-associated fibroblasts

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type

label

Macrophage migration inhibitor ...... cancer-associated fibroblasts

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Macrophage migration inhibitor ...... cancer-associated fibroblasts

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Macrophage migration inhibitor ...... cancer-associated fibroblasts

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Macrophage migration inhibitor ...... cancer-associated fibroblasts

@ast

Macrophage migration inhibitor ...... cancer-associated fibroblasts

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Macrophage migration inhibitor ...... cancer-associated fibroblasts

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1541-7786.MCR-10-0288

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Molecular Cancer Research

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Macrophage migration inhibitor ...... cancer-associated fibroblasts

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Janina Ratajczak

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Joanna Tarnowska

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Justyna Drukala

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Katarzyna Grymula

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Maciej Tarnowski

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Magda Kucia

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Robert A Mitchell

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Rui Liu

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P2860

Dual role of macrophage migration inhibitory factor (MIF) in human breast cancer

MIF signal transduction initiated by binding to CD74

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

A functional heteromeric MIF receptor formed by CD74 and CXCR4

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

Chemokines: a new classification system and their role in immunity

Macrophage migration inhibitory factor evaluation compared with prostate specific antigen as a biomarker in patients with prostate carcinoma.

Neural crest cell galvanotaxis: new data and a novel approach to the analysis of both galvanotaxis and chemotaxis.

Bone marrow CD34(+) cells and megakaryoblasts secrete beta-chemokines that block infection of hematopoietic cells by M-tropic R5 HIV.

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1328-1343

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10.1158/1541-7786.MCR-10-0288

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10

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8

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Mariusz Ratajczak

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2010-09-22T00:00:00Z

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46403191

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20861157

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2974061

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