7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats.
about
7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disordersInhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice.Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agents.Flavonoid Hesperidin Induces Synapse Formation and Improves Memory Performance through the Astrocytic TGF-β1.Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor.7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease.7,8-dihydroxyflavone, a small-molecule tropomyosin-related kinase B (TrkB) agonist, attenuates cerebral ischemia and reperfusion injury in rats.7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis.Exploring the Molecular Interactions of 7,8-Dihydroxyflavone and Its Derivatives with TrkB and VEGFR2 Proteins.Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels.Prefrontal cortical BDNF: A regulatory key in cocaine- and food-reinforced behaviors.Cognitive impairments following cranial irradiation can be mitigated by treatment with a tropomyosin receptor kinase B agonist.Synaptic regulation of affective behaviors; role of BDNF7,8-Dihydroxyflavone Ameliorates Cognitive Impairment by Inhibiting Expression of Tau Pathology in ApoE-Knockout Mice.Neurotrophic natural products: chemistry and biology.Aging impairs dendrite morphogenesis of newborn neurons and is rescued by 7, 8-dihydroxyflavoneTrkB activation by 7, 8-dihydroxyflavone increases synapse AMPA subunits and ameliorates spatial memory deficits in a mouse model of Alzheimer's disease.The Role of 7,8-Dihydroxyflavone in Preventing Dendrite Degeneration in Cortex After Moderate Traumatic Brain Injury.The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer's disease.Biosynthesis of novel 7,8-dihydroxyflavone glycoside derivatives and in silico study of their effects on BACE1 inhibition.Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer's disease.
P2860
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P2860
7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@ast
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@en
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@nl
type
label
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@ast
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@en
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@nl
prefLabel
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@ast
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@en
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@nl
P2093
P2860
P1476
7,8-dihydroxyflavone rescues s ...... ognitively impaired aged rats.
@en
P2093
P2860
P304
P356
10.1111/J.1471-4159.2012.07830.X
P407
P577
2012-07-09T00:00:00Z