Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration. - Wikidata - wikimedia - TriplyDB

Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration.

Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration.

http://www.wikidata.org/entity/Q34284175

about

The potential of sarcospan in adhesion complex replacement therapeutics for the treatment of muscular dystrophy A comparative study of N-glycolylneuraminic acid (Neu5Gc) and cytotoxic T cell (CT) carbohydrate expression in normal and dystrophin-deficient dog and human skeletal muscle From Nutrient to MicroRNA: a Novel Insight into Cell Signaling Involved in Skeletal Muscle Development and Disease The Dystrophin Complex: Structure, Function, and Implications for Therapy Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD.MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms Muscle structure influences utrophin expression in mdx mice.Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin.Single Cell Multiplex Protein Measurements through Rare Earth Element Immunolabeling, Laser Capture Microdissection and Inductively Coupled Mass Spectrometry Deletion of Galgt2 (B4Galnt2) reduces muscle growth in response to acute injury and increases muscle inflammation and pathology in dystrophin-deficient mice Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice.Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F.Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.Sarcospan: a small protein with large potential for Duchenne muscular dystrophy Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy-Associated Cardiomyopathy Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy Mitochondrial alterations and oxidative stress in an acute transient mouse model of muscle degeneration: implications for muscular dystrophy and related muscle pathologies.Vascular delivery of rAAVrh74.MCK.GALGT2 to the gastrocnemius muscle of the rhesus macaque stimulates the expression of dystrophin and laminin α2 surrogates.Finding the sweet spot: assembly and glycosylation of the dystrophin-associated glycoprotein complex.Comparison of skeletal muscle miRNA and mRNA profiles among three pig breeds.Differentiation-related glycan epitopes identify discrete domains of the muscle glycocalyx.Deletion of growth hormone receptors in postnatal skeletal muscle of male mice does not alter muscle mass and response to pathological injury.Mending a Broken Heart: The Role of Sarcospan in Duchenne Muscular Dystrophy-Associated Cardiomyopathy.Lectin-binding characterizes the healthy human skeletal muscle glycophenotype and identifies disease-specific changes in dystrophic muscle.Repression of phosphatidylinositol transfer protein α ameliorates the pathology of Duchenne muscular dystrophy.ECM-Related Myopathies and Muscular Dystrophies: Pros and Cons of Protein Therapies.Genetic modifiers of Duchenne and facioscapulohumeral muscular dystrophies.Protein disulfide isomerase as a prosurvival factor in cell therapy for muscular and vascular diseases

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Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration.

http://www.wikidata.org/entity/Q34284175

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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name

Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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Sarcospan-dependent Akt activa ...... ssion and muscle regeneration.

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P2093

Amber C Ocampo

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Angela K Peter

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Eric Chou

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Jamie L Marshall

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Jennifer Oh

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Johan Holmberg

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Joy Lee

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Paul T Martin

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Rachelle H Crosbie-Watson

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P2860

Structural determinants of integrin recognition by talin

Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy

Sarcospan, the 25-kDa transmembrane component of the dystrophin-glycoprotein complex

Sarcospan-deficient mice maintain normal muscle function

Molecular and genetic characterization of sarcospan: insights into sarcoglycan-sarcospan interactions

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

An autosomal transcript in skeletal muscle with homology to dystrophin

Human dystroglycan: skeletal muscle cDNA, genomic structure, origin of tissue specific isoforms and chromosomal localization

Molecular recognition by LARGE is essential for expression of functional dystroglycan

Synaptic integrins in developing, adult, and mutant muscle: selective association of alpha1, alpha7A, and alpha7B integrins with the neuromuscular junction

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1009-1027

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10.1083/JCB.201110032

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7

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197

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22734004

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3384411

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