Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants.
about
Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signalingOpiate pharmacology and relief of pain.Pharmacologic characterization in the rat of a potent analgesic lacking respiratory depression, IBNtxA.Opioids and their receptors: Are we there yet?Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine StimulationMediation of opioid analgesia by a truncated 6-transmembrane GPCR.Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behaviorInvestigating the effects of a hydrolytically stable hapten and a Th1 adjuvant on heroin vaccine performance.Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS.Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action.Mu opioids and their receptors: evolution of a concept.Novel 6β-acylaminomorphinans with analgesic activity.Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids.Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia.Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants.Activation of TREK-1 by morphine results in analgesia without adverse side effects.Truncated μ-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia.To probe interaction of morphine and IBNtxA with 7TM and 6TM variants of the human μ-opioid receptor using all-atom molecular dynamics simulations with an explicit membrane.Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
P2860
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P2860
Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Synthesis and evaluation of ar ...... eptor (MOR-1) splice variants.
@ast
Synthesis and evaluation of ar ...... eptor (MOR-1) splice variants.
@en
Synthesis and evaluation of ar ...... 1-associated μ opioid receptor
@nl
type
label
Synthesis and evaluation of ar ...... eptor (MOR-1) splice variants.
@ast
Synthesis and evaluation of ar ...... eptor (MOR-1) splice variants.
@en
Synthesis and evaluation of ar ...... 1-associated μ opioid receptor
@nl
prefLabel
Synthesis and evaluation of ar ...... eptor (MOR-1) splice variants.
@ast
Synthesis and evaluation of ar ...... eptor (MOR-1) splice variants.
@en
Synthesis and evaluation of ar ...... 1-associated μ opioid receptor
@nl
P2093
P2860
P356
P1476
Synthesis and evaluation of ar ...... eptor (MOR-1) splice variants.
@en
P2093
Anna R Pasternak
Gavril W Pasternak
Joan Subrath
Julie Ocampo
Kuni Nagakura
Lisa Polikar
Maxim Burgman
Nathan Haselton
Steven Grinnell
Susruta Majumdar
P2860
P304
P356
10.1021/JM300305C
P407
P577
2012-07-16T00:00:00Z