Splice variants of SmgGDS control small GTPase prenylation and membrane localization - Wikidata - wikimedia - TriplyDB

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

http://www.wikidata.org/entity/Q34284968

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Membrane phospholipid redistribution in cancer micro-particles and implications in the recruitment of cationic protein factors.A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins.Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer.sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs.SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.An adenosine-mediated signaling pathway suppresses prenylation of the GTPase Rap1B and promotes cell scattering.The SmgGDS splice variant SmgGDS-558 is a key promoter of tumor growth and RhoA signaling in breast cancer.Di-Ras2 Protein Forms a Complex with SmgGDS Protein in Brain Cytosol in Order to Be in a Low Affinity State for Guanine Nucleotides.The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif.SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers.Regulating the regulator: post-translational modification of RAS Recent advances in protein prenyltransferases: substrate identification, regulation, and disease interventions.Chaperone-mediated specificity in Ras and Rap signaling.Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding.Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B.Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells.Phosphorylation of Rac1 T108 by extracellular signal-regulated kinase in response to epidermal growth factor: a novel mechanism to regulate Rac1 function Control of RhoA methylation by carboxylesterase I Arg188 drives RhoC membrane binding.Meta-Analysis of Tourette Syndrome and Attention Deficit Hyperactivity Disorder Provides Support for a Shared Genetic Basis.Ras hitchhikes on PDE6δ.A new signaling paradigm to control the prenylation and trafficking of small GTPases Posttranslational Modifications of RAS Proteins.Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression.Cyclase-Associated Protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase.Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway The Many Faces of Rap1 GTPase

P2860

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P2860

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

http://www.wikidata.org/entity/Q34284968

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@ast

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@en

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@nl

type

label

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@ast

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@en

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@nl

prefLabel

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@ast

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@en

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@nl

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JBC.M110.129916

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Journal of Biological Chemistry

P1476

Splice variants of SmgGDS control small GTPase prenylation and membrane localization

@en

P2093

Adam J Gastonguay

http://www.w3.org/2001/XMLSchema#string

Alan P Fields

http://www.w3.org/2001/XMLSchema#string

Carol L Williams

http://www.w3.org/2001/XMLSchema#string

Ellen L Lorimer

http://www.w3.org/2001/XMLSchema#string

John R Kuhnmuench

http://www.w3.org/2001/XMLSchema#string

Rongshan Li

http://www.w3.org/2001/XMLSchema#string

Tracy J Berg

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction

Molecular cloning of the human cDNA for a stimulatory GDP/GTP exchange protein for c-Ki-ras p21 and smg p21

Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product

Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA

A repeating amino acid motif shared by proteins with diverse cellular roles

All ras proteins are polyisoprenylated but only some are palmitoylated

Implication of geranylgeranyltransferase I in synapse formation

Identification and characterization of the unique guanine nucleotide exchange factor, SmgGDS, in vascular smooth muscle cells

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

Involvement of a small GTP-binding protein (G protein) regulator, small G protein GDP dissociation stimulator, in antiapoptotic cell survival signaling

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35255-35266

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scholarly article

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10.1074/JBC.M110.129916

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46

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285

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2010-08-13T00:00:00Z

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20709748

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2975149

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