BRAF inactivation drives aneuploidy by deregulating CRAF
about
B-RAF mutant alleles associated with Langerhans cell histiocytosis, a granulomatous pediatric diseaseRaf kinases in cancer-roles and therapeutic opportunitiesThe intermediate-activity (L597V)BRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathwayBRAF kinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-type RAS.An Update on the Biology of RAS/RAF Mutations in Colorectal Cancer.A MEK-independent role for CRAF in mitosis and tumor progression.The cholesterol-binding protein NPC2 restrains recruitment of stromal macrophage-lineage cells to early-stage lung tumours.Activation loop phosphorylation regulates B-Raf in vivo and transformation by B-Raf mutants.Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutationsHuman endogenous retroviral K element encodes fusogenic activity in melanoma cells.Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinibA case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma.Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720.Mechanisms of aneuploidy induction by RAS and RAF oncogenesThe cancer biology of whole-chromosome instability.Vemurafenib in melanoma.The preclinical development of regorafenib for the treatment of colorectal cancer.Two Case Reports of Rare BRAF Mutations in Exon 11 and Exon 15 with Discussion of Potential Treatment Options.Molecular signaling in multiple myeloma: association of RAS/RAF mutations and MEK/ERK pathway activation.KRASG12D expression in lung-resident myeloid cells promotes pulmonary LCH-like neoplasm sensitive to statin treatment.Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib.RAF-isotype switching: from B to C through PDE.A Braf kinase-inactive mutant induces lung adenocarcinoma.High resolution melting analysis for detection of BRAF exon 15 mutations in hairy cell leukaemia and other lymphoid malignancies.
P2860
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P2860
BRAF inactivation drives aneuploidy by deregulating CRAF
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
BRAF inactivation drives aneuploidy by deregulating CRAF
@ast
BRAF inactivation drives aneuploidy by deregulating CRAF
@en
BRAF inactivation drives aneuploidy by deregulating CRAF
@nl
type
label
BRAF inactivation drives aneuploidy by deregulating CRAF
@ast
BRAF inactivation drives aneuploidy by deregulating CRAF
@en
BRAF inactivation drives aneuploidy by deregulating CRAF
@nl
prefLabel
BRAF inactivation drives aneuploidy by deregulating CRAF
@ast
BRAF inactivation drives aneuploidy by deregulating CRAF
@en
BRAF inactivation drives aneuploidy by deregulating CRAF
@nl
P2093
P2860
P1433
P1476
BRAF inactivation drives aneuploidy by deregulating CRAF
@en
P2093
Jahan Hussain
Robert Hayward
Susan Giblett
Tamihiro Kamata
P2860
P304
P356
10.1158/0008-5472.CAN-10-0603
P407
P577
2010-10-26T00:00:00Z