Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs. - Wikidata - wikimedia - TriplyDB

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

http://www.wikidata.org/entity/Q34289307

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GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human disease HSPA5/Dna K may be a useful target for human disease therapies.PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer OSU-03012 and Viagra Treatment Inhibits the Activity of Multiple Chaperone Proteins and Disrupts the Blood-Brain Barrier: Implications for Anti-Cancer Therapies GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases.Celecoxib enhances [sorafenib + sildenafil] lethality in cancer cells and reverts platinum chemotherapy resistance Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling.ABCG1 maintains high-grade glioma survival in vitro and in vivo.Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo.Phase I study of pemetrexed with sorafenib in advanced solid tumors.Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome.AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.[Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3-PI3K-NFκB compensatory survival signaling.AR-12 Inhibits Chaperone Proteins Preventing Virus Replication and the Accumulation of Toxic Misfolded Proteins.Effect of glycosides of Cistanche on the expression of mitochondrial precursor protein and keratin type II cytoskeletal 6A in a rat model of vascular dementia.Mouse low-grade gliomas contain cancer stem cells with unique molecular and functional properties.The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions.Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies.Beyond Alkylating Agents for Gliomas: Quo Vadimus?Repurposing drugs in oncology (ReDO)-selective PDE5 inhibitors as anti-cancer agents.

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P2860

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

http://www.wikidata.org/entity/Q34289307

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

@ast

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

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Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

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type

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Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

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Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

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Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

@nl

prefLabel

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

@ast

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

@en

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

@nl

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1535-7163.MCT-14-0172

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Molecular Cancer Therapeutics

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Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs.

@en

P2093

Andrew Poklepovic

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Jane L Roberts

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Laurence Booth

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Nichola Cruickshanks

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Steven Grant

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P2860

The selective Cox-2 inhibitor Celecoxib suppresses angiogenesis and growth of secondary bone tumors: an intravital microscopy study in mice

ER stress-induced cell death mechanisms

Adenocarcina of the mouse prostate growth inhibition by celecoxib: downregulation of transcription factors involved in COX-2 inhibition

COX-2 inhibition and colorectal cancer

PDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cells

Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide

Overall cardiovascular profile of sildenafil citrate

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway

Type 5 phosphodiesterase expression is a critical determinant of the endothelial cell angiogenic phenotype.

Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.

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2384-2398

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scholarly article

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10.1158/1535-7163.MCT-14-0172

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