about
The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53Camptothecin-induced downregulation of MLL5 contributes to the activation of tumor suppressor p53Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoformsPhysical interaction and mutual transrepression between CCAAT/enhancer-binding protein beta and the p53 tumor suppressorDNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramerAcetylation of lysine 382 and phosphorylation of serine 392 in p53 modulate the interaction between p53 and MDC1 in vitroStructural evolution of C-terminal domains in the p53 familyp53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum ConceptArginine methylation regulates the p53 responseActivation of p53 by protein inhibitor of activated Stat1 (PIAS1)Specific recognition of p53 tetramers by peptides derived from p53 interacting proteinsRecombinant p53 displays heterogeneity during isoelectric focusing.Synthetic ligands able to interact with the p53 tetramerization domain. Towards understanding a protein surface recognition event.Noncanonical DNA motifs as transactivation targets by wild type and mutant p53Parallel analysis of tetramerization domain mutants of the human p53 protein using PCR colonies.Oscillations of the p53-Akt network: implications on cell survival and deathCombining Oncolytic Virotherapy with p53 Tumor Suppressor Gene TherapyTP53 mutations in Korean patients with non-small cell lung cancer.Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor.The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis.Targeting protein inactivation through an oligomerization chain reactionTracing the protectors path from the germ line to the genome.Complementation of two mutant p53: implications for loss of heterozygosity in cancer.Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivationLikelihood models of somatic mutation and codon substitution in cancer genes.The DNA binding activity of p53 displays reaction-diffusion kinetics.A novel radiation-induced p53 mutation is not implicated in radiation resistance via a dominant-negative effect.Regulation of p53 localization and activity by Ubc13.The complex interactions of p53 with target DNA: we learn as we go.Protein domain-level landscape of cancer-type-specific somatic mutations.Mutant p53 promotes tumor cell malignancy by both positive and negative regulation of the transforming growth factor β (TGF-β) pathway.The cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.Integrative analysis of the microRNA-mRNA response to radiochemotherapy in primary head and neck squamous cell carcinoma cellsMolecular dynamic simulation insights into the normal state and restoration of p53 function.Genomic profiling of multiple sequentially acquired tumor metastatic sites from an "exceptional responder" lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment responseThe functional domains in p53 family proteins exhibit both common and distinct properties.Disruption of an intermonomer salt bridge in the p53 tetramerization domain results in an increased propensity to form amyloid fibrils.Lsc activity is controlled by oligomerization and regulates integrin adhesion.Stability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligand.HEXIM1, a New Player in the p53 Pathway
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The role of tetramerization in p53 function.
@ast
The role of tetramerization in p53 function.
@en
The role of tetramerization in p53 function.
@nl
type
label
The role of tetramerization in p53 function.
@ast
The role of tetramerization in p53 function.
@en
The role of tetramerization in p53 function.
@nl
prefLabel
The role of tetramerization in p53 function.
@ast
The role of tetramerization in p53 function.
@en
The role of tetramerization in p53 function.
@nl
P2860
P356
P1433
P1476
The role of tetramerization in p53 function.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204373
P407
P577
2001-05-01T00:00:00Z
P5875
P6179
1025353103