Opioid activation of toll-like receptor 4 contributes to drug reinforcement
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Neuroimmune mechanisms of stress: sex differences, developmental plasticity, and implications for pharmacotherapy of stress-related diseaseTargeting Toll-like receptors with small molecule agentsOpioid-induced central immune signaling: implications for opioid analgesiaGlucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced painMorphine induces redox-based changes in global DNA methylation and retrotransposon transcription by inhibition of excitatory amino acid transporter type 3-mediated cysteine uptake.Stimulants as specific inducers of dopamine-independent σ agonist self-administration in ratsToll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivationToll-like receptor 4 mutant and null mice retain morphine-induced tolerance, hyperalgesia, and physical dependence.Toll-like receptor 4 (TLR4) modulation by synthetic and natural compounds: an update.Acute morphine alters GABAergic transmission in the central amygdala during naloxone-precipitated morphine withdrawal: role of cyclic AMP.Toll-like Receptor-Dependent Negative Effects of Opioids: A Battle between Analgesia and Hyperalgesia.FACS analysis of neuronal-glial interactions in the nucleus accumbens following morphine administration.Medication-overuse headache and opioid-induced hyperalgesia: A review of mechanisms, a neuroimmune hypothesis and a novel approach to treatment.Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in ratsExplaining human recreational use of 'pesticides': The neurotoxin regulation model of substance use vs. the hijack model and implications for age and sex differences in drug consumption.Preliminary pharmacological evaluation of enantiomeric morphinans.Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelaeCodeine-induced hyperalgesia and allodynia: investigating the role of glial activationSelect steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced painChronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6.Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling.Sex differences in motivational responses to dietary fat in Syrian hamstersGene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling.Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists.Application of calibrated forceps for assessing mechanical nociception with high time resolution in mice.Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague-Dawley rats.Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving.Morphine-enhanced apoptosis in selective brain regions of neonatal ratsMorphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a.Adolescent morphine exposure affects long-term microglial function and later-life relapse liability in a model of addictionComparison of (+)- and (-)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Acetylmorphine, and Morphine in Mice.CCL5 and cytokine expression in the rat brain: differential modulation by chronic morphine and morphine withdrawal.Why is neuroimmunopharmacology crucial for the future of addiction research?Withdrawal-associated injury site pain (WISP): a descriptive case series of an opioid cessation phenomenon.A structural insight into the negative effects of opioids in analgesia by modulating the TLR4 signaling: An in silico approach.Lack of Effects of Toll-Like Receptor 4 Antagonists on the Reinforcing Effects of Cocaine and Remifentanil.Allostatic Mechanisms of Opioid Tolerance Beyond Desensitization and DownregulationThe effect of gut microbiome on tolerance to morphine mediated antinociception in mice.
P2860
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P2860
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@ast
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@en
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@nl
type
label
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@ast
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@en
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@nl
prefLabel
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@ast
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@en
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@nl
P2093
P2860
P50
P1476
Opioid activation of toll-like receptor 4 contributes to drug reinforcement
@en
P2093
A A Somogyi
A L Northcutt
C Sfregola
K van Steeg
P2860
P304
11187-11200
P356
10.1523/JNEUROSCI.0684-12.2012
P407
P577
2012-08-01T00:00:00Z