Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specific interactions between the alpha-subunits.
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Amino-terminal determinants of U-type inactivation of voltage-gated K+ channelsObligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2The human delta1261 mutation of the HERG potassium channel results in a truncated protein that contains a subunit interaction domain and decreases the channel expressionMutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4Functional co-assembly among subunits of cyclic-nucleotide-activated, nonselective cation channels, and across species from nematode to human.Domain analysis of Kv6.3, an electrically silent channelDimerization of TWIK-1 K+ channel subunits via a disulfide bridgeFunctional coupling of intracellular calcium and inactivation of voltage-gated Kv1.1/Kvbeta1.1 A-type K+ channelsDeterminant for beta-subunit regulation in high-conductance voltage-activated and Ca(2+)-sensitive K+ channels: an additional transmembrane region at the N terminusKv5, Kv6, Kv8, and Kv9 subunits: No simple silent bystandersSubunit composition of Kv1 channels in human CNSVoltage-gated ion channel Kv4.3 is associated with Rap guanine nucleotide exchange factors and regulates angiotensin receptor type 1 signaling to small G-protein RapKCNE1 and KCNE2 provide a checkpoint governing voltage-gated potassium channel α-subunit compositionKCNE2 and the K (+) channel: the tail wagging the dogSelective interaction of voltage-gated K+ channel beta-subunits with alpha-subunitsEndogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studiesKv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel currentCarboxy-terminal domain mediates assembly of the voltage-gated rat ether-à-go-go potassium channelKinesin I transports tetramerized Kv3 channels through the axon initial segment via direct bindingActivation of conventional kinesin motors in clusters by Shaw voltage-gated K+ channels.The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic HomeostasisModular organization of the PDZ domains in the human discs-large protein suggests a mechanism for coupling PDZ domain-binding proteins to ATP and the membrane cytoskeleton.Pleiotropic effects of a disrupted K+ channel gene: reduced body weight, impaired motor skill and muscle contraction, but no seizures.Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels.Preferential KAT1-KAT2 heteromerization determines inward K+ current properties in Arabidopsis guard cells.Tetramerization domain mutations in KCNA5 affect channel kinetics and cause abnormal trafficking patterns.Molecular diversity and regulation of renal potassium channels.Functional rescue of Kv4.3 channel tetramerization mutants by KChIP4a.K+ channel inactivation mediated by the concerted action of the cytoplasmic N- and C-terminal domains.Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells.Assembly of ROMK1 (Kir 1.1a) inward rectifier K+ channel subunits involves multiple interaction sitesShaker and ether-à-go-go K+ channel subunits fail to coassemble in Xenopus oocytes.Evidence for dimerization of dimers in K+ channel assembly.Inactivation and pharmacological properties of sqKv1A homotetramers in Xenopus oocytes cannot account for behavior of the squid "delayed rectifier" K(+) conductanceExpanded functional diversity of shaker K(+) channels in cnidarians is driven by gene expansion.Made for "anchorin": Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons.An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1Major diversification of voltage-gated K+ channels occurred in ancestral parahoxozoans.The subfamily-specific interaction between Kv2.1 and Kv6.4 subunits is determined by interactions between the N- and C-termini.
P2860
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P2860
Assembly of voltage-gated potassium channels. Conserved hydrophilic motifs determine subfamily-specific interactions between the alpha-subunits.
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@ast
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@en
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@nl
type
label
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@ast
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@en
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@nl
prefLabel
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@ast
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@en
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@nl
P2093
P2860
P356
P1476
Assembly of voltage-gated pota ...... ns between the alpha-subunits.
@en
P2093
P2860
P304
24761-24768
P356
10.1074/JBC.270.42.24761
P407
P577
1995-10-01T00:00:00Z