Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity

Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity

Item
http://www.wikidata.org/entity/Q34297181
RXFP1 is Targeted by Complement C1q Tumor Necrosis Factor-Related Factor 8 in Brain CancerSeasonal oscillation of liver-derived hibernation protein complex in the central nervous system of non-hibernating mammalsTranscriptional regulation of an insulin-sensitizing adipokine adipolin/CTRP12 in adipocytes by Krüppel-like factor 15.C1q-TNF-related protein-9, a novel cardioprotetcive cardiokine, requires proteolytic cleavage to generate a biologically active globular domain isoform.CTRP3 deficiency reduces liver size and alters IL-6 and TGFβ levels in obese mice.CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism.CTRP9 transgenic mice are protected from diet-induced obesity and metabolic dysfunction.Neutrophil elastase cleavage of the gC1q domain impairs the EMILIN1-α4β1 integrin interaction, cell adhesion and anti-proliferative activityC1q/TNF-related protein 4 (CTRP4) is a unique secreted protein with two tandem C1q domains that functions in the hypothalamus to modulate food intake and body weight.Metabolic function of the CTRP family of hormones.Targeted deletion of C1q/TNF-related protein 9 increases food intake, decreases insulin sensitivity, and promotes hepatic steatosis in miceAdipokines and insulin action: A sensitive issue.Structural commonality of C1q TNF-related proteins and their potential to activate relaxin/insulin-like family peptide receptor 1 signalling pathways in cancer cells.Impact of caloric restriction on myocardial ischaemia/reperfusion injury and new therapeutic options to mimic its effectsPartial deficiency of CTRP12 alters hepatic lipid metabolism.CTRP7 deletion attenuates obesity-linked glucose intolerance, adipose tissue inflammation, and hepatic stress.
P2860

Endopeptidase cleavage generates a functionally distinct isoform of C1q/tumor necrosis factor-related protein-12 (CTRP12) with an altered oligomeric state and signaling specificity

Item
http://www.wikidata.org/entity/Q34297181
description
2012 nî lūn-bûn
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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Endopeptidase cleavage generat ...... tate and signaling specificity
@ast
Endopeptidase cleavage generat ...... tate and signaling specificity
@en
Endopeptidase cleavage generat ...... osis factor-related protein-12
@nl
type
label
Endopeptidase cleavage generat ...... tate and signaling specificity
@ast
Endopeptidase cleavage generat ...... tate and signaling specificity
@en
Endopeptidase cleavage generat ...... osis factor-related protein-12
@nl
prefLabel
Endopeptidase cleavage generat ...... tate and signaling specificity
@ast
Endopeptidase cleavage generat ...... tate and signaling specificity
@en
Endopeptidase cleavage generat ...... osis factor-related protein-12
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Endopeptidase cleavage generat ...... tate and signaling specificity
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932