Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications.
about
The human 20-kDa 5'-(CGG)(n)-3'-binding protein is targeted to the nucleus and affects the activity of the FMR1 promoterMultiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiaeB-chromosome evolutionFragile X (CGG)n repeats induce a transcriptional repression in cis upon a linked promoter: evidence for a chromatin mediated effectLength-dependent energetics of (CTG)n and (CAG)n trinucleotide repeats.Transgene-induced CCWGG methylation does not alter CG methylation patterning in human kidney cells.Repeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disordersA MutSβ-Dependent Contribution of MutSα to Repeat Expansions in Fragile X Premutation Mice?Development of Genetic Testing for Fragile X Syndrome and Associated Disorders, and Estimates of the Prevalence of FMR1 Expansion MutationsG-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeGenetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.Molecular basis of genetic instability of triplet repeatsSedimentation analysis of novel DNA structures formed by homo-oligonucleotides.Transcription-associated R-loop formation across the human FMR1 CGG-repeat regionRole of the closing base pair for d(GCA) hairpin stability: free energy analysis and folding simulations.Tetraplex formation by the progressive myoclonus epilepsy type-1 repeat: implications for instability in the repeat expansion diseases.De novo methylation and co-suppression induced by a cytoplasmically replicating plant RNA virusDNA secondary structure: a common and causative factor for expansion in human disease.Interruption of the fragile X syndrome expanded sequence d(CGG)(n) by interspersed d(AGG) trinucleotides diminishes the formation and stability of d(CGG)(n) tetrahelical structuresUnusual mutations in high functioning fragile X males: apparent instability of expanded unmethylated CGG repeats.Stable secondary structure near the nicking site for adeno-associated virus type 2 Rep proteins on human chromosome 19Expansions and contractions in a tandem repeat induced by double-strand break repair.G-quadruplex nucleic acids and human diseaseHypomethylation of an expanded FMR1 allele is not associated with a global DNA methylation defect.Secondary structure at a hot spot for DNA methylation in DNA from human breast cancers.Methylation and colorectal cancer.Conformational energetics of stable and metastable states formed by DNA triplet repeat oligonucleotides: implications for triplet expansion diseasesDisruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disordersTowards understanding the epigenetics of transcription by chromatin structure and the nuclear matrix.Structure and dynamics of the DNA hairpins formed by tandemly repeated CTG triplets associated with myotonic dystrophy.Solution structures of the individual single strands of the fragile X DNA triplets (GCC)n.(GGC)nLong inverted repeats are an at-risk motif for recombination in mammalian cells.Cloned human FMR1 trinucleotide repeats exhibit a length- and orientation-dependent instability suggestive of in vivo lagging strand secondary structure.NGG-triplet repeats form similar intrastrand structures: implications for the triplet expansion diseases.The purine-rich trinucleotide repeat sequences d(CAG)15 and d(GAC)15 form hairpinsCompound microsatellite repeats: practical and theoretical featuresMeiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.Double-strand breaks in the myotonic dystrophy type 1 and the fragile X syndrome triplet repeat sequences induce different types of mutations in DNA flanking sequences in Escherichia coli.Different mechanisms underlie DNA instability in Huntington disease and colorectal cancerHijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease.
P2860
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P2860
Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Hairpins are formed by the sin ...... e and biological implications.
@ast
Hairpins are formed by the sin ...... e and biological implications.
@en
Hairpins are formed by the sin ...... e and biological implications.
@nl
type
label
Hairpins are formed by the sin ...... e and biological implications.
@ast
Hairpins are formed by the sin ...... e and biological implications.
@en
Hairpins are formed by the sin ...... e and biological implications.
@nl
prefLabel
Hairpins are formed by the sin ...... e and biological implications.
@ast
Hairpins are formed by the sin ...... e and biological implications.
@en
Hairpins are formed by the sin ...... e and biological implications.
@nl
P2093
P2860
P356
P1476
Hairpins are formed by the sin ...... e and biological implications.
@en
P2093
E M Bradbury
R K Moyzis
S V Mariappan
P2860
P304
P356
10.1073/PNAS.92.11.5199
P407
P577
1995-05-01T00:00:00Z