Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer. - Wikidata - wikimedia - TriplyDB

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

http://www.wikidata.org/entity/Q34303695

about

The role of suppressors of cytokine signalling in human neoplasms Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers Adult hair follicle stem cells do not retain the older DNA strands in vivo during normal tissue homeostasis Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in mice Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer Clinical impact of tumour biology in the management of gastroesophageal cancer Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasion Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.Runx1 contributes to neurofibromatosis type 1 neurofibroma formation.Runx1: no longer just for leukemia ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity.Runx1 and p21 synergistically limit the extent of hair follicle stem cell quiescence in vivo The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion.Gene-set Analysis with CGI Information for Differential DNA Methylation Profiling RUNX1 and FOXP3 interplay regulates expression of breast cancer related genes New insights into the role of Runx1 in epithelial stem cell biology and pathology.SOCS proteins in development and disease.Posttranslational modifications of RUNX1 as potential anticancer targets.The RUNX family: developmental regulators in cancer.The enigmatic role of RUNX1 in female-related cancers - current knowledge & future perspectives.Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression.Runx3 in Immunity, Inflammation and Cancer.Runx Family Genes in Tissue Stem Cell Dynamics.Runx Genes in Breast Cancer and the Mammary Lineage.Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus.High Runx1 levels promote a reversible, more-differentiated cell state in hair-follicle stem cells during quiescence.Runt-related Transcription Factor 1 (RUNX1) Binds to p50 in Macrophages and Enhances TLR4-triggered Inflammation and Septic Shock.miR-500a-3p promotes cancer stem cells properties via STAT3 pathway in human hepatocellular carcinoma A missense mutation underlies defective SOCS4 function in a family with autoimmunity.The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling.The miR-101/RUNX1 feedback regulatory loop modulates chemo-sensitivity and invasion in human lung cancer.HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers.Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity.RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells.Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma.Genetic variants in the JAK1 gene confer higher risk of Behcet's disease with ocular involvement in Han Chinese.RUNX1 regulates transcription of genes involved in differentiation of keratinocytes Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions.A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells.

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Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

http://www.wikidata.org/entity/Q34303695

description

2012 nî lūn-bûn

@nan

2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@ast

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@en

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@nl

type

label

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@ast

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@en

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@nl

prefLabel

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@ast

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@en

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.

@nl

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The EMBO Journal

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Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer

@en

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Cornelia Johanna Franziska Scheitz

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David James McDermitt

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Tae Seung Lee

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P2860

Generalized lacZ expression with the ROSA26 Cre reporter strain

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

The RUNX genes: gain or loss of function in cancer

Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments

The STATs of cancer--new molecular targets come of age

Stat3 as an oncogene

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

Cells of origin in cancer

Identifying significant genetic regulatory networks in the prostate cancer from microarray data based on transcription factor analysis and conditional independency

Targeted disruption of stat3 reveals a major role for follicular stem cells in skin tumor initiation.

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4124-4139

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10.1038/EMBOJ.2012.270

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21

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31

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Tudorita Tumbar

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2012-10-02T00:00:00Z

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232008769

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23034403

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3492731

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