A role for Rac in Tiam1-induced membrane ruffling and invasion.
about
Activation of Rac1 by a Crk SH3-binding protein, DOCK180Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligandsRac1-induced cell migration requires membrane recruitment of the nuclear oncogene SETNon-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9A mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domainTargeting and activation of Rac1 are mediated by the exchange factor beta-Pix.Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7Ack1 mediates Cdc42-dependent cell migration and signaling to p130CasRhoG signals in parallel with Rac1 and Cdc42CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteinsThe multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domainsRhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreasThe PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding moduleNegative regulation of Rho family GTPases Cdc42 and Rac2 by homodimer formationHuman enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiaeIdentification of a novel Rac1-interacting protein involved in membrane rufflingThe F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development.VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of TiamActivation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targetingMembrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascadeKinectin is a key effector of RhoG microtubule-dependent cellular activityOligomerization of DH domain is essential for Dbl-induced transformationWrch-1, a novel member of the Rho gene family that is regulated by Wnt-1RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42HsRegulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activationAnkyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migrationTiam1 transgenic mice display increased tumor invasive and metastatic potential of colorectal cancer after 1,2-dimethylhydrazine treatmentP-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironmentsHuman Mena associates with Rac1 small GTPase in glioblastoma cell linesStructure and mutagenesis of the Dbl homology domainRom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteinsIntegrins as receptors for lamininsInteraction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factorsTrp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factorsXPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC
P2860
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P2860
A role for Rac in Tiam1-induced membrane ruffling and invasion.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@ast
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@en
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@nl
type
label
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@ast
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@en
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@nl
prefLabel
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@ast
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@en
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@nl
P2093
P356
P1433
P1476
A role for Rac in Tiam1-induced membrane ruffling and invasion.
@en
P2093
Collard JG
Michiels F
van der Kammen RA
P2888
P304
P356
10.1038/375338A0
P407
P577
1995-05-01T00:00:00Z
P6179
1006273973