The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo.
about
Structure of precursor microRNA's terminal loop regulates human Dicer's dicing activity by switching DExH/D domainDicer-TRBP complex formation ensures accurate mammalian microRNA biogenesisPost-Translational Regulation of miRNA Pathway Components, AGO1 and HYL1, in PlantsBone Marrow Gene Therapy for HIV/AIDSVersatile microRNA biogenesis in animals and their virusesRibonuclease III mechanisms of double-stranded RNA cleavageGenetic variants in microRNA genes: impact on microRNA expression, function, and diseaseA Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human DicerStructure of a Eukaryotic RNase III Postcleavage Complex Reveals a Double-Ruler Mechanism for Substrate SelectionTranscriptome wide annotation of eukaryotic RNase III reactivity and degradation signalsOrganic small hairpin RNAs (OshR): a do-it-yourself platform for transgene-based gene silencing.The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation siteGenome-wide miRNA seeds prediction in Archaea.VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.Small RNA sequence analysis of adenovirus VA RNA-derived miRNAs reveals an unexpected serotype-specific difference in structure and abundanceMammalian 5'-capped microRNA precursors that generate a single microRNA.A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cellsWeak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs.PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors.Comparative analysis of RNAi screening technologies at genome-scale reveals an inherent processing inefficiency of the plasmid-based shRNA hairpinEntropy-based model for miRNA isoform analysis.Development of gene therapy for treatment of age-related macular degeneration.Discovery of a dicer-independent, cell-type dependent alternate targeting sequence generator: implications in gene silencing & pooled RNAi screens.Synergistic inhibition of avian leukosis virus subgroup J replication by miRNA-embedded siRNA interference of double-target.A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications.Sequence features of Drosha and Dicer cleavage sites affect the complexity of isomiRsHigh-throughput functional genomics using CRISPR-Cas9.Towards Antiviral shRNAs Based on the AgoshRNA Design.The many faces of Dicer: the complexity of the mechanisms regulating Dicer gene expression and enzyme activitiesAlleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys.The host Integrator complex acts in transcription-independent maturation of herpesvirus microRNA 3' ends.MiRNA-Embedded ShRNAs for Radiation-Inducible LGMN Knockdown and the Antitumor Effects on Breast Cancer.The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes.LBSizeCleav: improved support vector machine (SVM)-based prediction of Dicer cleavage sites using loop/bulge length.Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effectsA streamlined method for the design and cloning of shRNAs into an optimized Dox-inducible lentiviral vector.Prediction of potent shRNAs with a sequential classification algorithm.Nucleotide sequence of miRNA precursor contributes to cleavage site selection by Dicer.Expression profile of Epstein-Barr virus and human adenovirus small RNAs in tonsillar B and T lymphocytes.In vivo RNAi screens: concepts and applications.
P2860
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P2860
The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The loop position of shRNAs an ...... y of dicer processing in vivo.
@ast
The loop position of shRNAs an ...... y of dicer processing in vivo.
@en
The loop position of shRNAs an ...... y of dicer processing in vivo.
@nl
type
label
The loop position of shRNAs an ...... y of dicer processing in vivo.
@ast
The loop position of shRNAs an ...... y of dicer processing in vivo.
@en
The loop position of shRNAs an ...... y of dicer processing in vivo.
@nl
prefLabel
The loop position of shRNAs an ...... y of dicer processing in vivo.
@ast
The loop position of shRNAs an ...... y of dicer processing in vivo.
@en
The loop position of shRNAs an ...... y of dicer processing in vivo.
@nl
P2093
P2860
P1433
P1476
The loop position of shRNAs an ...... y of dicer processing in vivo.
@en
P2093
P2860
P304
P356
10.1016/J.CELL.2012.09.042
P407
P577
2012-11-01T00:00:00Z