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Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

http://www.wikidata.org/entity/Q34312222

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Interaction of endosialin/TEM1 with extracellular matrix proteins mediates cell adhesion and migration The role of pericytes in blood-vessel formation and maintenance Pericyte-targeting drug delivery and tissue engineering The Role of NG2 Proteoglycan in Glioma The pericyte: a forgotten cell type with important implications for Alzheimer's disease?Pericyte dynamics during angiogenesis: new insights from new identities Diversified expression of NG2/CSPG4 isoforms in glioblastoma and human foetal brain identifies pericyte subsets Theranostic impact of NG2/CSPG4 proteoglycan in cancer Targeting pericytes for angiogenic therapies.Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2 Adult NG2+ cells are permissive to neurite outgrowth and stabilize sensory axons during macrophage-induced axonal dieback after spinal cord injury.Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity.Contribution of bone marrow-derived pericyte precursor cells to corneal vasculogenesis.Targeting pericytes diminishes neovascularization in orthotopic uveal melanoma in nerve/glial antigen 2 proteoglycan knockout mouse Central nervous system pericytes in health and disease.The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelination Myelin repair and functional recovery mediated by neural cell transplantation in a mouse model of multiple sclerosis.Targeting neovascular pericytes in neurofibromatosis type 1.NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature.Pericyte-derived MFG-E8 regulates pathologic angiogenesis Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord.Pericytes, microvasular dysfunction, and chronic rejection.Pericyte chemomechanics and the angiogenic switch: insights into the pathogenesis of proliferative diabetic retinopathy?The genetic control of avascular area in mouse oxygen-induced retinopathy Functional overlap between chondroitin and heparan sulfate proteoglycans during VEGF-induced sprouting angiogenesis.Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration.Hedgehog signaling indirectly affects tubular cell survival after obstructive kidney injury.Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan.NG2 Proteoglycan Ablation Reduces Foam Cell Formation and Atherogenesis via Decreased Low-Density Lipoprotein Retention by Synthetic Smooth Muscle Cells.An angiogenesis model for investigating multicellular interactions across intact microvascular networks.NG2 Proteoglycan-Dependent Contributions of Pericytes and Macrophages to Brain Tumor Vascularization and Progression.Multivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells.Early inhibition of MMP activity in ischemic rat brain promotes expression of tight junction proteins and angiogenesis during recovery.Tumor microenvironment in the brain Reversal of cellular roles in angiogenesis: implications for anti-angiogenic therapy.A simple method for measuring interstitial fluid pressure in cancer tissues.Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival A role for the NG2 proteoglycan in glioma progression.NG2 proteoglycan promotes tumor vascularization via integrin-dependent effects on pericyte function.The perivascular niche microenvironment in brain tumor progression.

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P2860

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

http://www.wikidata.org/entity/Q34312222

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունվարին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@ast

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@en

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@nl

type

label

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@ast

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@en

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@nl

prefLabel

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@ast

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@en

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

@nl

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Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

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Ugur Ozerdem

http://www.w3.org/2001/XMLSchema#string

William B Stallcup

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P2860

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis

Altering the genome by homologous recombination

Time course of endothelial cell proliferation and microvascular remodeling in chronic inflammation

NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis

Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain

Angiogenesis in cancer, vascular, rheumatoid and other disease

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Mechanisms of angiogenesis

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

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s10456-004-4182-6

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