Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer.

Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer.

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http://www.wikidata.org/entity/Q34313778
Deubiquitinating enzymes as oncotargetsA High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell ModelsDeubiquitinases in cancer.Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer.Chemical and semisynthetic approaches to study and target deubiquitinases.Mutations in the 'Fingers' subdomain of the deubiquitinase USP1 modulate its function and activity.Deubiquitylating enzymes and drug discovery: emerging opportunities.Highly electron-poor Buchwald-type ligand: application for Pd-catalysed direct arylation of thiophene derivatives and theoretical consideration of the secondary Pd(0)-arene interaction.The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival.
P2860

Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer.

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http://www.wikidata.org/entity/Q34313778
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2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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type
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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Synthesis and structure-activi ...... nst nonsmall cell lung cancer.
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P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932