The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. - Wikidata - wikimedia - TriplyDB

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.

http://www.wikidata.org/entity/Q34313840

about

DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 Resolution of Inflammation: What Controls Its Onset?Immunity and Tolerance Induced by Intestinal Mucosal Dendritic Cells Cytokine-Induced Modulation of Colorectal Cancer Immune Homeostasis in Epithelial Cells: Evidence and Role of Inflammasome Signaling Reviewed Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design Interleukin 1β-A Potential Salivary Biomarker for Cancer Progression?NLRP3 Inflammasome and Pathobiology in AMD New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation Development and survival of Th17 cells within the intestines: the influence of microbiome- and diet-derived signals NLRP6 in infection and inflammation NOD-Like Receptors: Master Regulators of Inflammation and Cancer Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis Intestinal barrier in inflammatory bowel disease Inflammasomes and intestinal homeostasis: regulating and connecting infection, inflammation and the microbiota Inflammasome in intestinal inflammation and cancer Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.Oligomannan Prebiotic Attenuates Immunological, Clinical and Behavioral Symptoms in Mouse Model of Inflammatory Bowel Disease.The inflammasome: an emerging therapeutic oncotarget for cancer prevention Cytokines, IBD, and colitis-associated cancer Holding the inflammatory system in check: NLRs keep it cool Bacterial recognition pathways that lead to inflammasome activation Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression Inflammasomes: caspase-1-activating platforms with critical roles in host defense Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury A functional role for Nlrp6 in intestinal inflammation and tumorigenesis The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer The inflammasome NLRs in immunity, inflammation, and associated diseases NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis Genetics and pathogenesis of inflammatory bowel disease Dedicator of Cytokinesis 2 in Cell Signaling Regulation and Disease Development.Dissemination of invasive Salmonella via bacterial-induced extrusion of mucosal epithelia.NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.Interactions between the host innate immune system and microbes in inflammatory bowel disease.Detrimental Impact of Microbiota-Accessible Carbohydrate-Deprived Diet on Gut and Immune Homeostasis: An Overview

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P2860

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.

http://www.wikidata.org/entity/Q34313840

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2010 nî lūn-bûn

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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Md Hasan Zaki

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Michael B Kastan

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Mohamed Lamkanfi

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P2860

Inflammatory Bowel Disease

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

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Thirumala-Devi Kanneganti

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