Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy.
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Human induced pluripotent stem cells for monogenic disease modelling and therapyALS Patient Stem Cells for Unveiling Disease Signatures of Motoneuron Susceptibility: Perspectives on the Deadly Mitochondria, ER Stress and Calcium TriadiPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease DevelopmentNeurodegenerative diseases in a dish: the promise of iPSC technology in disease modeling and therapeutic discoveryStem cells in the nervous systemAdvances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative DiseasesUtility of Induced Pluripotent Stem Cells for the Study and Treatment of Genetic Diseases: Focus on Childhood Neurological DisordersChondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophyCreating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture.Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines.Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog.Growth inhibitory effects and molecular mechanisms of crotoxin treatment in esophageal Eca-109 cells and transplanted tumors in nude mice.Patient-derived skeletal dysplasia induced pluripotent stem cells display abnormal chondrogenic marker expression and regulation by BMP2 and TGFβ1Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord.Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansionSensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophyAssays for the identification and prioritization of drug candidates for spinal muscular atrophyTranscriptome profiling of spinal muscular atrophy motor neurons derived from mouse embryonic stem cellsInvestigating human disease using stem cell models.Therapeutic opportunities and challenges of induced pluripotent stem cells-derived motor neurons for treatment of amyotrophic lateral sclerosis and motor neuron disease.Model systems of motor neuron diseases as a platform for studying pathogenic mechanisms and searching for therapeutic agents.Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins.HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.Advances in reprogramming-based study of neurologic disordersMagnetic resonance imaging of stem cell apoptosis in arthritic joints with a caspase activatable contrast agent.Probing disorders of the nervous system using reprogramming approaches.Spinal muscular atrophy patient-derived motor neurons exhibit hyperexcitability.iPSC technology--Powerful hand for disease modeling and therapeutic screenCharacterization of type I interferon pathway during hepatic differentiation of human pluripotent stem cells and hepatitis C virus infection.Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons.Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Have Reduced Expression of Proteins Important in Neuronal Development.Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy.Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells.Clinical Trials in a Dish: The Potential of Pluripotent Stem Cells to Develop Therapies for Neurodegenerative Diseases.Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor productionOne-Step Seeding of Neural Stem Cells with Vitronectin-Supplemented Medium for High-Throughput Screening Assays.Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neuronsSpinal muscular atrophy and the antiapoptotic role of survival of motor neuron (SMN) protein.
P2860
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P2860
Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@ast
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@en
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@nl
type
label
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@ast
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@en
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@nl
prefLabel
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@ast
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@en
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@nl
P2093
P2860
P1433
P1476
Inhibition of apoptosis blocks ...... el of spinal muscular atrophy.
@en
P2093
Allison D Ebert
Brittany M Heins
Clive N Svendsen
Dhruv Sareen
Jered V McGivern
Loren Ornelas
P2860
P304
P356
10.1371/JOURNAL.PONE.0039113
P407
P577
2012-06-19T00:00:00Z