Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy.
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Arginine Metabolism in Bacterial Pathogenesis and Cancer TherapyArginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.Arginine deprivation and autophagic cell death in cancerTetrandrine is a potent cell autophagy agonist via activated intracellular reactive oxygen speciesAutophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells.Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophyLong-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle.A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas.Genomewide copy number analysis of Müllerian adenosarcoma identified chromosomal instability in the aggressive subgroup.How does metabolism affect cell death in cancer?Drug-induced amino acid deprivation as strategy for cancer therapy.Nucleolar aggresomes mediate release of pericentric heterochromatin and nuclear destruction of genotoxically treated cancer cells.Molecular basis and current strategies of therapeutic arginine depletion for cancer.Selective Intracellular Delivery of Recombinant Arginine Deiminase (ADI) Using pH-Sensitive Cell Penetrating Peptides To Overcome ADI Resistance in Hypoxic Breast Cancer CellsArginine dependence of tumor cells: targeting a chink in cancer's armor.Mechanistic insights into selective autophagy pathways: lessons from yeast.Microenvironmental Effects of Cell Death in Malignant Disease.Arginine-Dual roles as an onconutrient and immunonutrient.PKCη deficiency improves lipid metabolism and atherosclerosis in apolipoprotein E-deficient mice.Identification of 7-(4'-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cellsMetabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells.Domesticating Cancer: An Evolutionary Strategy in the War on Cancer.CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway.Arginine Deprivation Inhibits the Warburg Effect and Upregulates Glutamine Anaplerosis and Serine Biosynthesis in ASS1-Deficient Cancers.Cargo recognition and degradation by selective autophagy.Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunctionRecombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer
P2860
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P2860
Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Arginine starvation-associated ...... kage, and chromatin autophagy.
@ast
Arginine starvation-associated ...... kage, and chromatin autophagy.
@en
Arginine starvation-associated ...... kage, and chromatin autophagy.
@nl
type
label
Arginine starvation-associated ...... kage, and chromatin autophagy.
@ast
Arginine starvation-associated ...... kage, and chromatin autophagy.
@en
Arginine starvation-associated ...... kage, and chromatin autophagy.
@nl
prefLabel
Arginine starvation-associated ...... kage, and chromatin autophagy.
@ast
Arginine starvation-associated ...... kage, and chromatin autophagy.
@en
Arginine starvation-associated ...... kage, and chromatin autophagy.
@nl
P2093
P2860
P356
P1476
Arginine starvation-associated ...... kage, and chromatin autophagy.
@en
P2093
Chun A Changou
David K Ann
Frank Y S Chuang
Hsing-Jien Kung
R Holland Cheng
Richard J Bold
Yun-Ru Chen
P2860
P304
14147-14152
P356
10.1073/PNAS.1404171111
P407
P577
2014-08-13T00:00:00Z