A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands - Wikidata - wikimedia - TriplyDB

A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands

A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands

http://www.wikidata.org/entity/Q34314581

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Glycosylated Notch and Cancer Notch-Mediated Cell Adhesion Targeting the Notch signaling pathway in cancer therapeutics Protein phosphatase 1ß limits ring canal constriction during Drosophila germline cyst formation The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration Negative regulation of notch signaling by xylose Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands Notch ligands regulate the muscle stem-like state ex vivo but are not sufficient for retaining regenerative capacity.Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster.The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit.Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11.Structural biology. Structural basis for Notch1 engagement of Delta-like 4 Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells.Blockade of specific NOTCH ligands: a new promising approach in cancer therapy Fruit flies in biomedical research.Competition in notch signaling with cis enriches cell fate decisions.Control of Neural Daughter Cell Proliferation by Multi-level Notch/Su(H)/E(spl)-HLH Signaling.Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.Xylosylation of the Notch receptor preserves the balance between its activation by trans-Delta and inhibition by cis-ligands in Drosophila.An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling.Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates.Therapeutic modulation of Notch signalling--are we there yet?Significance of glycosylation in Notch signaling.Building and specializing epithelial tubular organs: the Drosophila salivary gland as a model system for revealing how epithelial organs are specified, form and specialize.The multiple roles of epidermal growth factor repeat O-glycans in animal development.Mapping Sites of O-Glycosylation and Fringe Elongation on Drosophila Notch.The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands.(1)H, (13)C and (15)N assignments of EGF domains 8-11 of human Notch-1.Identification and characterization of a novel Sso7d scaffold-based binder against Notch1.Dual Roles of O-Glucose Glycans Redundant with Monosaccharide O-Fucose on Notch in Notch Trafficking.Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.Understanding the determinants of notch interactions with its ligands.Inhibition of Delta-induced Notch signaling using fucose analogs.Cell Aggregation Assays to Evaluate the Binding of the Drosophila Notch with Trans-Ligands and its Inhibition by Cis-Ligands.Signal Transduction: Notch catches a Jagged edge.1H, 13C and 15N assignments of EGF domains 4 to 7 of human Notch-1

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P2860

A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands

http://www.wikidata.org/entity/Q34314581

description

2012 nî lūn-bûn

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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年论文

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name

A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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A mutation in EGF repeat-8 of ...... agged and Delta family ligands

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Gabriela David

http://www.w3.org/2001/XMLSchema#string

Hao Wang

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Ke Zhang

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Nadia A Rana

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Robert S Haltiwanger

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Shinako Kakuda

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Wu-Lin Charng

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P2860

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

Novel NOTCH1 mutations in patients with bicuspid aortic valve disease and thoracic aortic aneurysms

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Fringe is a glycosyltransferase that modifies Notch

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium

The canonical Notch signaling pathway: unfolding the activation mechanism.

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1229-1232

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scholarly article

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10.1126/SCIENCE.1228745

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6111

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338

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Shinya Yamamoto

Hector Sandoval

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2012-11-01T00:00:00Z

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233806268

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23197537

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3663443

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