Interleukin 6 induces a liver-specific nuclear protein that binds to the promoter of acute-phase genes.
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A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP familyRegulation of serum amyloid A protein expression during the acute-phase responseDistinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa BHuman herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6.C/EBP transcription factors regulate NADPH oxidase in human aortic smooth muscle cells.Raised pro-inflammatory cytokines interleukin 6 and tumour necrosis factor alpha in coeliac disease mucosa detected by immunohistochemistry.Possibilities of DNA analysis for the detection of predisposition to thrombotic disease.Constitutive and modulated expression of the human alpha 1 antitrypsin gene. Different transcriptional initiation sites used in three different cell types.Paradoxical Immune Responses in Non-HIV Cryptococcal MeningitisCooperative effects of C/EBP-like and NF kappa B-like binding sites on rat serum amyloid A1 gene expression in liver cells.Oct-1 acts as a transcriptional repressor on the C-reactive protein promoterParticipation of the transcription factor C/EBP delta in the acute-phase regulation of the human gene for complement component C3Characterization and functional analysis of the human inducible nitric oxide synthase gene promoter.A novel cis-acting element is essential for cytokine-mediated transcriptional induction of the serum amyloid A gene in nonhepatic cellsEvidence for posttranscriptional regulation of C/EBPalpha and C/EBPbeta isoform expression during the lipopolysaccharide-mediated acute-phase response.Differentiated liver cell specificity of the second enhancer of hepatitis B virusInduction of the mouse serum amyloid A3 gene by cytokines requires both C/EBP family proteins and a novel constitutive nuclear factor.The warm temperature acclimation-related 65-kDa protein, Wap65, in goldfish and its gene expression.Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interactionRegulation of mouse serum amyloid A gene expression in transfected hepatoma cellsThe cytokine response element of the rat alpha 1-acid glycoprotein gene is a complex of several interacting regulatory sequencesDistinct regulation of the interleukin-1 and interleukin-6 response elements of the rat haptoglobin gene in rat and human hepatoma cells.C/EBP-like proteins binding to the functional box-alpha and box-beta of the second enhancer of hepatitis B virusA 58-base-pair region of the human C3 gene confers synergistic inducibility by interleukin-1 and interleukin-6.Synergistic action of interleukin-6 and glucocorticoids is mediated by the interleukin-6 response element of the rat alpha 2 macroglobulin geneInterleukin 6 enhances a cellular activity that functionally substitutes for E1A protein in transactivation.Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene.The transcription factor C/EBPbeta is essential for inducible expression of the cox-2 gene in macrophages but not in fibroblasts.Activation of the TSG-6 gene by NF-IL6 requires two adjacent NF-IL6 binding sites.The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements.Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.Liver-specific gene expression: A-activator-binding site, a promoter module present in vitellogenin and acute-phase genes.Interleukin-1-mediated enhancement of mouse factor B gene expression via NF kappa B-like hepatoma nuclear factor.Characterization of transcriptional regulatory elements in the promoter region of the murine blood coagulation factor VII gene.Regulation of HIV-1 long terminal repeats by interaction of C/EBP(NF-IL6) and NF-kappaB/Rel transcription factors.Genetic organization of two types of flounder warm-temperature acclimation-associated 65-kDa protein and their gene expression profiles.CCAAT/enhancer-binding protein α is a crucial regulator of human fat mass and obesity associated gene transcription and expression.The two C/EBP isoforms, IL-6DBP/NF-IL6 and C/EBP delta/NF-IL6 beta, are induced by IL-6 to promote acute phase gene transcription via different mechanisms.Liver specific transcription factors of the HNF3-, C/EBP- and LFB1-families interact with the A-activator binding site.
P2860
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P2860
Interleukin 6 induces a liver-specific nuclear protein that binds to the promoter of acute-phase genes.
description
1989 nî lūn-bûn
@nan
1989 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@ast
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@en
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@nl
type
label
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@ast
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@en
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@nl
prefLabel
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@ast
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@en
Interleukin 6 induces a liver- ...... promoter of acute-phase genes.
@nl
P2860
P356
P1476
Interleukin 6 induces a liver- ...... promoter of acute-phase genes
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.21.8202
P407
P50
P577
1989-11-01T00:00:00Z