HTLV-1 tax-induced rapid senescence is driven by the transcriptional activity of NF-κB and depends on chronically activated IKKα and p65/RelA.

HTLV-1 tax-induced rapid senescence is driven by the transcriptional activity of NF-κB and depends on chronically activated IKKα and p65/RelA.

Item
http://www.wikidata.org/entity/Q34319511
Highlights on distinctive structural and functional properties of HTLV Tax proteinsHTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZModes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and PersistenceAcetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation.Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax.Permissive Sense and Antisense Transcription from the 5' and 3' Long Terminal Repeats of Human T-Cell Leukemia Virus Type 1NF-κB inhibition facilitates the establishment of cell lines that chronically produce human T-lymphotropic virus type 1 viral particlesRegulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.Human T cell leukemia virus type I tax-induced IκB-ζ modulates tax-dependent and tax-independent gene expression in T cells.Oncogenic spiral by infectious pathogens: Cooperation of multiple factors in cancer development.Stability of the HTLV-1 Antisense-Derived Protein, HBZ, Is Regulated by the E3 Ubiquitin-Protein Ligase, UBR5.The TP53-Induced Glycolysis and Apoptosis Regulator mediates cooperation between HTLV-1 p30II and the retroviral oncoproteins Tax and HBZ and is highly expressed in an in vivo xenograft model of HTLV-1-induced lymphoma.
P2860

HTLV-1 tax-induced rapid senescence is driven by the transcriptional activity of NF-κB and depends on chronically activated IKKα and p65/RelA.

Item
http://www.wikidata.org/entity/Q34319511
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@ast
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@en
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@nl
type
label
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@ast
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@en
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@nl
prefLabel
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@ast
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@en
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
HTLV-1 tax-induced rapid senes ...... y activated IKKα and p65/RelA.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932