Overexpression, purification, and characterization of VanX, a D-, D-dipeptidase which is essential for vancomycin resistance in Enterococcus faecium BM4147.
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Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms.Structural basis for the evolution of vancomycin resistance D,D-peptidasesPhosphinate analogs of D-, D-dipeptides: slow-binding inhibition and proteolysis protection of VanX, a D-, D-dipeptidase required for vancomycin resistance in Enterococcus faecium.VanX, a bacterial D-alanyl-D-alanine dipeptidase: resistance, immunity, or survival function?Vancomycin-resistant enterococci.Two-step acquisition of resistance to the teicoplanin-gentamicin combination by VanB-type Enterococcus faecalis in vitro and in experimental endocarditisA periplasmic D-alanyl-D-alanine dipeptidase in the gram-negative bacterium Salmonella entericaOvercoming antimicrobial resistance by targeting resistance mechanisms.Bacterial resistance to vancomycin: overproduction, purification, and characterization of VanC2 from Enterococcus casseliflavus as a D-Ala-D-Ser ligase.VanD-type glycopeptide-resistant Enterococcus faecium BM4339.Probing the reaction mechanism of the D-ala-D-ala dipeptidase, VanX, by using stopped-flow kinetic and rapid-freeze quench EPR studies on the Co(II)-substituted enzyme.Streptomyces spp. as efficient expression system for a D,D-peptidase/D,D-carboxypeptidase involved in glycopeptide antibiotic resistanceExperimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.Mechanism of action of oritavancin and related glycopeptide antibiotics.The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction.Vancomycin resistance in enterococci due to synthesis of precursors terminating in D-alanyl-D-serine.D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanBCross-talk between the histidine protein kinase VanS and the response regulator PhoB. Characterization and identification of a VanS domain that inhibits activation of PhoB.Characteristics of a new enantioselective thermostable dipeptidase from Brevibacillus borstelensis BCS-1 and its application to synthesis of a D-amino-acid-containing dipeptide.Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria.New β-phospholactam as a carbapenem transition state analog: Synthesis of a broad-spectrum inhibitor of metallo-β-lactamasesDirected evolution of Pseudomonas aeruginosa lipase for improved amide-hydrolyzing activity.Old and New Glycopeptide Antibiotics: Action and Resistance.Glycopeptide-resistant Enterococcus faecium BM4416 is a VanD-type strain with an impaired D-Alanine:D-Alanine ligaseDdlN from vancomycin-producing Amycolatopsis orientalis C329.2 is a VanA homologue with D-alanyl-D-lactate ligase activity.Substrate Inhibition of VanA by d-Alanine Reduces Vancomycin Resistance in a VanX-Dependent Manner.Inhibition of peptidoglycan biosynthesis in vancomycin-susceptible and -resistant bacteria by a semisynthetic glycopeptide antibiotic.Heterologous expression of the enterococcal vanA operon in methicillin-resistant Staphylococcus aureus.A thioredoxin fusion protein of VanH, a D-lactate dehydrogenase from Enterococcus faecium: cloning, expression, purification, kinetic analysis, and crystallization.Resistance to glycopeptide antibiotics in the teicoplanin producer is mediated by van gene homologue expression directing the synthesis of a modified cell wall peptidoglycan.Relationship between glycopeptide production and resistance in the actinomycete Nonomuraea sp. ATCC 39727.Purification and characterization of VanXY(C), a D,D-dipeptidase/D,D-carboxypeptidase in vancomycin-resistant Enterococcus gallinarum BM4174.Characterization of VanYn, a novel D,D-peptidase/D,D-carboxypeptidase involved in glycopeptide antibiotic resistance in Nonomuraea sp. ATCC 39727.D-Alanyl-D-lactate and D-alanyl-D-alanine synthesis by D-alanyl-D-alanine ligase from vancomycin-resistant Leuconostoc mesenteroides. Effects of a phenylalanine 261 to tyrosine mutation.Requirement of the VanY and VanX D,D-peptidases for glycopeptide resistance in enterococci.
P2860
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P2860
Overexpression, purification, and characterization of VanX, a D-, D-dipeptidase which is essential for vancomycin resistance in Enterococcus faecium BM4147.
description
1995 nî lūn-bûn
@nan
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@ast
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@en
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@nl
type
label
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@ast
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@en
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@nl
prefLabel
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@ast
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@en
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@nl
P356
P1433
P1476
Overexpression, purification, ...... n Enterococcus faecium BM4147.
@en
P304
P356
10.1021/BI00008A008
P407
P577
1995-02-01T00:00:00Z