Discovery of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using virtual screening and scaffold hopping.

Discovery of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using virtual screening and scaffold hopping.

Item
http://www.wikidata.org/entity/Q34319990
Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virusModification of S-Adenosyl-l-Homocysteine as Inhibitor of Nonstructural Protein 5 Methyltransferase Dengue Virus Through Molecular Docking and Molecular Dynamics Simulation.The flavivirus protease as a target for drug discovery.A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 proteaseBenzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase.Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells.Identification of covalent active site inhibitors of dengue virus protease.Targeting host factors to treat West Nile and dengue viral infections.Virtual-screening targeting Human Immunodeficiency Virus type 1 integrase-lens epithelium-derived growth factor/p75 interaction for drug development.Live Cell Reporter Systems for Positive-Sense Single Strand RNA Viruses.3D-QSAR pharmacophore-based virtual screening, molecular docking and molecular dynamics simulation toward identifying lead compounds for NS2B-NS3 protease inhibitors.In vitro evaluation of novel inhibitors against the NS2B-NS3 protease of dengue fever virus type 4.Structure-guided Discovery of a Novel Non-peptide Inhibitor of Dengue Virus NS2B-NS3 Protease.
P2860

Discovery of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using virtual screening and scaffold hopping.

Item
http://www.wikidata.org/entity/Q34319990
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Discovery of novel small molec ...... creening and scaffold hopping.
@ast
Discovery of novel small molec ...... creening and scaffold hopping.
@en
Discovery of novel small molec ...... creening and scaffold hopping.
@nl
type
label
Discovery of novel small molec ...... creening and scaffold hopping.
@ast
Discovery of novel small molec ...... creening and scaffold hopping.
@en
Discovery of novel small molec ...... creening and scaffold hopping.
@nl
prefLabel
Discovery of novel small molec ...... creening and scaffold hopping.
@ast
Discovery of novel small molec ...... creening and scaffold hopping.
@en
Discovery of novel small molec ...... creening and scaffold hopping.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Discovery of novel small molec ...... creening and scaffold hopping.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921