SKF83959 is a potent allosteric modulator of sigma-1 receptor.
about
Dopamine D1 receptor signaling: does GαQ-phospholipase C actually play a role?Allosteric Modulation of Sigma-1 Receptors Elicits Rapid Antidepressant ActivitySKF-83959 is not a highly-biased functionally selective D1 dopamine receptor ligand with activity at phospholipase CD1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms.Effects of SKF83959 on the excitability of hippocampal CA1 pyramidal neurons: a modeling study.The cognition-enhancing activity of E1R, a novel positive allosteric modulator of sigma-1 receptorsIdentification of G protein-biased agonists that fail to recruit β-arrestin or promote internalization of the D1 dopamine receptor.SKF83959 produces antidepressant effects in a chronic social defeat stress model of depression through BDNF-TrkB pathway.The dopamine D1-D2 receptor heteromer exerts a tonic inhibitory effect on the expression of amphetamine-induced locomotor sensitization.Regulation of c-fos expression by the dopamine D1-D2 receptor heteromer.Allosteric modulation of sigma-1 receptors elicits anti-seizure activitiesIdentification of the Sigma-2 Receptor: Distinct from the Progesterone Receptor Membrane Component 1 (PGRMC1).Selective sigma-1 receptor antagonists for the treatment of pain.The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction.Recent Advances in the Realm of Allosteric Modulators for Opioid Receptors for Future Therapeutics.Allosteric modulation of sigma-1 receptors by SKF83959 inhibits microglia-mediated inflammation.Role of σ1 Receptors in Learning and Memory and Alzheimer's Disease-Type Dementia.Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB.Age-Dependent D1-D2 Receptor Coactivation in the Lateral Orbitofrontal Cortex Potentiates NMDA Receptors and Facilitates Cognitive Flexibility.The Role of Sigma-1 Receptor, an Intracellular Chaperone in Neurodegenerative Diseases.Sigma-1 Receptor-Modulated Neuroinflammation in Neurological Diseases
P2860
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P2860
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@ast
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@en
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@nl
type
label
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@ast
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@en
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@nl
prefLabel
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@ast
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@en
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@nl
P2093
P356
P1476
SKF83959 is a potent allosteric modulator of sigma-1 receptor.
@en
P2093
Guanghui Wang
Guozhang Jin
Jianghao Zhao
Xuechu Zhen
P304
P356
10.1124/MOL.112.083840
P577
2013-01-07T00:00:00Z