Structural insights for engineering binding proteins based on non-antibody scaffolds
about
Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicityDissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domainsSelection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and XaperonesETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formationProtein-Protein Interactions Mediated by Helical Tertiary Structure Motifs.Nanobodies as Probes for Protein Dynamics in Vitro and in Cells.Monobodies and other synthetic binding proteins for expanding protein scienceSelective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.Strategies to control the binding mode of de novo designed protein interactions.Structural basis of IL-23 antagonism by an Alphabody protein scaffoldDevelopment and characterization of small bispecific albumin-binding domains with high affinity for ErbB3.Fibronectin type III domains engineered to bind CD40L: cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of two complexesA transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screenHow structure defines affinity in protein-protein interactions.Aromatic cluster mutations produce focal modulations of β-sheet structure.Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5.Specific GFP-binding artificial proteins (αRep): a new tool for in vitro to live cell applicationsDelivery of antibody mimics into mammalian cells via anthrax toxin protective antigenPhage display selection of tight specific binding variants from a hyperthermostable Sso7d scaffold protein library.Directed Evolution of FLS2 towards Novel Flagellin Peptide Recognition.Engineered Autonomous Human Variable DomainsOrganometallic palladium reagents for cysteine bioconjugationAllosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase InterfaceGeneration of high-performance binding proteins for peptide motifs by affinity clampingDesign of an expression system to enhance MBP-mediated crystallizationSystematic Targeting of Protein-Protein InteractionsSynthetic Protein Switches: Theoretical and Experimental Considerations.Novel binders derived from an albumin-binding domain scaffold targeting human prostate secretory protein 94 (PSP94)Hierarchical design of artificial proteins and complexes toward synthetic structural biology.Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP-9 and MMP-14.Non-Antibody Scaffolds as Alternative Therapeutic AgentsA recipe for ligand-binding proteins
P2860
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P2860
Structural insights for engineering binding proteins based on non-antibody scaffolds
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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name
Structural insights for engineering binding proteins based on non-antibody scaffolds
@ast
Structural insights for engineering binding proteins based on non-antibody scaffolds
@en
Structural insights for engineering binding proteins based on non-antibody scaffolds
@nl
type
label
Structural insights for engineering binding proteins based on non-antibody scaffolds
@ast
Structural insights for engineering binding proteins based on non-antibody scaffolds
@en
Structural insights for engineering binding proteins based on non-antibody scaffolds
@nl
prefLabel
Structural insights for engineering binding proteins based on non-antibody scaffolds
@ast
Structural insights for engineering binding proteins based on non-antibody scaffolds
@en
Structural insights for engineering binding proteins based on non-antibody scaffolds
@nl
P2860
P1476
Structural insights for engineering binding proteins based on non-antibody scaffolds
@en
P2093
Ryan N Gilbreth
P2860
P304
P356
10.1016/J.SBI.2012.06.001
P50
P577
2012-06-27T00:00:00Z