A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas. - Wikidata - wikimedia - TriplyDB

A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas.

A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas.

http://www.wikidata.org/entity/Q34332525

about

DIPG in Children - What Can We Learn from the Past?Advances in the management of paediatric high-grade glioma.Differences in molecular genetics between pediatric and adult malignant astrocytomas: age matters.Management of diffuse pontine gliomas in children: recent developments.Phase 2 study of safety and efficacy of nimotuzumab in pediatric patients with progressive diffuse intrinsic pontine glioma.Brainstem glioma: a review.A phase II study of gefitinib and irradiation in children with newly diagnosed brainstem gliomas: a report from the Pediatric Brain Tumor Consortium.Synergistic antitumor effect between gefitinib and fractionated irradiation in anaplastic oligodendrogliomas cannot be predicted by the Egfr signaling activity.Radiation myelitis after hypofractionated radiotherapy with concomitant gefitinib.Management of high-grade gliomas in the pediatric patient: Past, present, and future.Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma.Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma Genomic aberrations in pediatric diffuse intrinsic pontine gliomas Neurotoxicity of biologically targeted agents in pediatric cancer trials Combining molecular targeted agents with radiation therapy for malignant gliomas Nimotuzumab for pediatric diffuse intrinsic pontine gliomas.Treatment of high-grade glioma in children and adolescents.Paediatric and adult malignant glioma: close relatives or distant cousins?Overcoming the blood-brain barrier in chemotherapy treatment of pediatric brain tumors.Pediatric diffuse intrinsic pontine glioma: can optimism replace pessimism?Diffuse intrinsic pontine glioma: time for therapeutic optimism.Commentary on: "A Multi-Institutional Experience in Pediatric High Grade Glioma".Screening candidate anticancer drugs for brain tumor chemotherapy: pharmacokinetic-driven approach for a series of (E)-N-(substituted aryl)-3-(substituted phenyl)propenamide analogues.Proceedings of the diffuse intrinsic pontine glioma (DIPG) Toronto Think Tank: advancing basic and translational research and cooperation in DIPG.Antigen-specific immunoreactivity and clinical outcome following vaccination with glioma-associated antigen peptides in children with recurrent high-grade gliomas: results of a pilot study.

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A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas.

http://www.wikidata.org/entity/Q34332525

description

2010 nî lūn-bûn

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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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A phase I and biology study of ...... ratentorial malignant gliomas.

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J.EJCA.2010.07.005

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European Journal of Cancer

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A phase I and biology study of ...... ratentorial malignant gliomas.

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Anu Banerjee

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Clinton F Stewart

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J Russell Geyer

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James G Douglas

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James M Boyett

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Roger J Packer

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Sri Gururangan

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P2860

Deletion-mutant epidermal growth factor receptor in human gliomas: effects of type II mutation on receptor function

Functionally defective or altered CYP3A4 and CYP3A5 single nucleotide polymorphisms and their detection with genotyping tests

Diffuse brain stem glioma. A review of stereotactic biopsies.

Conversion of a radioresistant phenotype to a more sensitive one by disabling erbB receptor signaling in human cancer cells

The epidermal growth factor receptor and its inhibition in cancer therapy.

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

Intratumoral hemorrhage among children with newly diagnosed, diffuse brainstem glioma.

ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase I trial.

Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types.

ERBB1 is amplified and overexpressed in high-grade diffusely infiltrative pediatric brain stem glioma.

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Alberto Broniscer

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45649701

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