The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers.

The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers.

Item
http://www.wikidata.org/entity/Q34333184
Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical applicationTwo distinct but interchangeable mechanisms for flipping of lipid-linked oligosaccharidesRole of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein.Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeableA single amino acid substitution in CFTR converts ATP to an inhibitory ligand.ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum.Insight in eukaryotic ABC transporter function by mutation analysis.Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Converting nonhydrolyzable nucleotides to strong cystic fibrosis transmembrane conductance regulator (CFTR) agonists by gain of function (GOF) mutationsMutations at the signature sequence of CFTR create a Cd(2+)-gated chloride channel.CLC-0 and CFTR: chloride channels evolved from transporters.ATP-driven MalK dimer closure and reopening and conformational changes of the "EAA" motifs are crucial for function of the maltose ATP-binding cassette transporter (MalFGK2).Attempts to characterize the NBD heterodimer of MRP1: transient complex formation involves Gly771 of the ABC signature sequence but does not enhance the intrinsic ATPase activity.The linker region of breast cancer resistance protein ABCG2 is critical for coupling of ATP-dependent drug transport.Functionally Relevant Residues of Cdr1p: A Multidrug ABC Transporter of Human Pathogenic Candida albicans.Novel roles for ATP-binding cassette G transporters in lipid redistribution in Toxoplasma.
P2860

The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers.

Item
http://www.wikidata.org/entity/Q34333184
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The role of the conserved glyc ...... ite and the catalytic centers.
@ast
The role of the conserved glyc ...... ite and the catalytic centers.
@en
The role of the conserved glyc ...... ite and the catalytic centers.
@nl
type
label
The role of the conserved glyc ...... ite and the catalytic centers.
@ast
The role of the conserved glyc ...... ite and the catalytic centers.
@en
The role of the conserved glyc ...... ite and the catalytic centers.
@nl
prefLabel
The role of the conserved glyc ...... ite and the catalytic centers.
@ast
The role of the conserved glyc ...... ite and the catalytic centers.
@en
The role of the conserved glyc ...... ite and the catalytic centers.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
The role of the conserved glyc ...... site and the catalytic centers
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698