The multicellular tumor spheroid model for high-throughput cancer drug discovery.
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AlgiMatrix™ based 3D cell culture system as an in-vitro tumor model for anticancer studiesIn Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right PlatformModulation of the tumor microenvironment for cancer treatment: a biomaterials approachHigh content screening in chemical biology: overview and main challengesColorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in cultureApplication of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance modelHigh-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional modelsLive multicellular tumor spheroid models for high-content imaging and screening in cancer drug discovery.Time-lapse 3-D measurements of a glucose biosensor in multicellular spheroids by light sheet fluorescence microscopy in commercial 96-well plates.Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study.Sialylation facilitates self-assembly of 3D multicellular prostaspheres by using cyclo-RGDfK(TPP) peptide.Mechanistic characterization of a copper containing thiosemicarbazone with potent antitumor activity.Screening candidate metastasis-associated genes in three-dimensional HCC spheroids with different metastasis potential.Three-dimensional in vitro tumor models for cancer research and drug evaluation.High Throughput, Polymeric Aqueous Two-Phase Printing of Tumor Spheroids.An HTS-compatible 3D colony formation assay to identify tumor-specific chemotherapeutics.Quantitative determination of irinotecan and the metabolite SN-38 by nanoflow liquid chromatography-tandem mass spectrometry in different regions of multicellular tumor spheroids.Synthetic tumor networks for screening drug delivery systemsQuantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.Challenges and opportunities toward enabling phenotypic screening of complex and 3D cell models.High-throughput imaging: Focusing in on drug discovery in 3D.Ultrahigh-throughput Generation and Characterization of Cellular Aggregates in Laser-ablated Microwells of Poly(dimethylsiloxane).Robotic production of cancer cell spheroids with an aqueous two-phase system for drug testingMicrocapsules and 3D customizable shelled microenvironments from laser direct-written microbeads.Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis.Linking hypoxia, DNA damage and proliferation in multicellular tumor spheroidsGetting to know ovarian cancer ascites: opportunities for targeted therapy-based translational research.Biomimetic on-a-chip platforms for studying cancer metastasisTopoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancerShape matters: the diffusion rates of TMV rods and CPMV icosahedrons in a spheroid model of extracellular matrix are distinctIn situ gelation for cell immobilization and culture in alginate foam scaffolds.Alternative therapies for metastatic breast cancer: multimodal approach targeting tumor cell heterogeneity.New horizons in therapeutic antibody discovery: opportunities and challenges versus small-molecule therapeutics.Getting the whole picture: High content screening using three-dimensional cellular model systems and whole animal assays.Mesenchymal Stem Cells Relevance in Multicellular Bioengineered 3D In vitro Tumor Models.Intravital imaging of a spheroid-based orthotopic model of melanoma in the mouse ear skin.Real-time viability and apoptosis kinetic detection method of 3D multicellular tumor spheroids using the Celigo Image Cytometer.Development of an in vitro tumor spheroid culture model amenable to high-throughput testing of potential anticancer nanotherapeutics.Towards personalized medicine: chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform.Three-dimensional co-culture of hepatic progenitor cells and mesenchymal stem cells in vitro and in vivo.
P2860
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P2860
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@ast
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@en
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@nl
type
label
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@ast
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@en
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@nl
prefLabel
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@ast
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@en
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@nl
P2093
P2860
P1476
The multicellular tumor spheroid model for high-throughput cancer drug discovery.
@en
P2093
Brian G Reid
Byong Hoon Yoo
Daniel V LaBarbera
P2860
P304
P356
10.1517/17460441.2012.708334
P407
P577
2012-07-12T00:00:00Z