Inhibition of amyloid fibril formation by peptide analogues modified with alpha-aminoisobutyric acid.
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Molecular basis for insulin fibril assemblyMolecular Structure, Membrane Interactions, and Toxicity of the Islet Amyloid Polypeptide in Type 2 Diabetes MellitusFormation of bacterial pilus-like nanofibres by designed minimalistic self-assembling peptides.Quantitative structure-activity relationship analysis of β-amyloid aggregation inhibitors.Peptides for therapy and diagnosis of Alzheimer's disease.Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesisIon mobility spectrometry-mass spectrometry defines the oligomeric intermediates in amylin amyloid formation and the mode of action of inhibitorsPhenol red interacts with the protofibril-like oligomers of an amyloidogenic hexapeptide NFGAIL through both hydrophobic and aromatic contacts.Effects of peptides derived from terminal modifications of the aβ central hydrophobic core on aβ fibrillization.Formation of functional super-helical assemblies by constrained single heptad repeatThe influence of phospholipid membranes on bovine calcitonin secondary structure and amyloid formationConformationally restricted short peptides inhibit human islet amyloid polypeptide (hIAPP) fibrillization.Self assembly of short aromatic peptides into amyloid fibrils and related nanostructures.A survey of peptides with effective therapeutic potential in Alzheimer's disease rodent models or in human clinical studies.Therapeutic strategies against protein misfolding in neurodegenerative diseases.Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid stateInhibition of amyloid oligomerization into different supramolecular architectures by small molecules: mechanistic insights and design rules.Rational design of an orthosteric regulator of hIAPP aggregation.The importance of being Aib. Aggregation and self-assembly studies on conformationally constrained oligopeptides.The role of the 14-20 domain of the islet amyloid polypeptide in amyloid formationReversal of aggregation using β-breaker dipeptide containing peptides: Application to Aβ(1-40) self-assembly and its inhibition.Disaggregation of Amylin Aggregate by Novel Conformationally Restricted Aminobenzoic Acid containing α/β and α/γ Hybrid Peptidomimetics.A Degraded Fragment of HIV-1 Gp120 in Rat Hepatocytes Forms Fibrils and Enhances HIV-1 Infection.Rationally designed peptidomimetic modulators of aβ toxicity in Alzheimer's disease.Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitorDesign of an N-methylated peptide inhibitor of alpha-synuclein aggregation guided by solid-state NMR.Enantioselective organocatalytic addition of oxazolones to 1,1-bis(phenylsulfonyl)ethylene: a convenient asymmetric synthesis of quaternary alpha-amino acids.Binding Interactions of Agents That Alter α-Synuclein Aggregation.NAP alpha-aminoisobutyric acid (IsoNAP).Inhibition of Alzheimer's amyloid-β peptide aggregation and its disruption by a conformationally restricted α/β hybrid peptide.An ultrafast molecular rotor based ternary complex in a nanocavity: a potential "turn on" fluorescence sensor for the hydrocarbon chain.(R)-α-trifluoromethylalanine containing short peptide in the inhibition of amyloid peptide fibrillationThe generic amyloid formation inhibition effect of a designed small aromatic β-breaking peptideA single-residue substitution inhibits fibrillization of Ala-based pentapeptides. A spectroscopic and molecular dynamics investigationRole and Cytotoxicity of Amylin and Protection of Pancreatic Islet β-Cells from Amylin Cytotoxicity
P2860
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P2860
Inhibition of amyloid fibril formation by peptide analogues modified with alpha-aminoisobutyric acid.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@ast
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@en
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@nl
type
label
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@ast
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@en
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@nl
prefLabel
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@ast
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@en
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@nl
P356
P1476
Inhibition of amyloid fibril f ...... th alpha-aminoisobutyric acid.
@en
P2093
Ehud Gazit
Sharon Gilead
P304
P356
10.1002/ANIE.200353565
P407
P577
2004-08-01T00:00:00Z