Regioselective arene halogenation using the FAD-dependent halogenase RebH.
about
Insights into enzymatic halogenation from computational studiesImproving the Stability and Catalyst Lifetime of the Halogenase RebH By Directed EvolutionA Structure-Guided Switch in the Regioselectivity of a Tryptophan HalogenaseThe Oxygen Dilemma: A Severe Challenge for the Application of Monooxygenases?Halogenase-Inspired Oxidative Chlorination Using Flavin PhotocatalysisEnzymatic halogenation of tryptophan on a gram scale.Directed evolution of RebH for site-selective halogenation of large biologically active molecules.Directed Evolution of RebH for Catalyst-Controlled Halogenation of Indole C-H BondsA High-Throughput Fluorescence Assay to Determine the Activity of Tryptophan Halogenases.A Simple Combinatorial Codon Mutagenesis Method for Targeted Protein EngineeringDirect C7 Functionalization of Tryptophan. Synthesis of Methyl (S)-2-((tert-Butoxycarbonyl)amino)-3-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-3-yl)propanoate.Halogenase Engineering for the Generation of New Natural Product Analogues.Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.Specific Enzymatic Halogenation-From the Discovery of Halogenated Enzymes to Their Applications In Vitro and In Vivo.Enzymatic Halogenation: A Timely Strategy for Regioselective C-H Activation.Regioselective Dichlorination of a Non-Activated Aliphatic Carbon Atom and Phenolic Bismethylation by a Multifunctional Fungal Flavoenzyme.Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan AnaloguesIntegrated catalysis opens new arylation pathways via regiodivergent enzymatic C-H activation.C7-derivatization of C3-alkylindoles including tryptophans and tryptamines.Late-Stage Diversification of Biologically Active Molecules via Chemoenzymatic C-H Functionalization.Understanding Flavin-Dependent Halogenase Reactivity via Substrate Activity Profiling.RadH: A Versatile Halogenase for Integration into Synthetic Pathways.A high-throughput assay for arylamine halogenation based on a peroxidase-mediated quinone-amine coupling with applications in the screening of enzymatic halogenations.Catalyst-Controlled Site-Selective Bond Activation.Function and Structure of MalA/MalA', Iterative Halogenases for Late-Stage C-H Functionalization of Indole Alkaloids.Aromatic Halogenation by Using Bifunctional Flavin Reductase-Halogenase Fusion Enzymes.Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.Recombinant flavin-dependent halogenases are functional in tobacco chloroplasts without co-expression of flavin reductase genes.Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes.Understanding and Improving the Activity of Flavin-Dependent Halogenases via Random and Targeted Mutagenesis.Two-Component FAD-Dependent Monooxygenases: Current Knowledge and Biotechnological Opportunities
P2860
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P2860
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
description
2013 nî lūn-bûn
@nan
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@ast
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@en
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@nl
type
label
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@ast
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@en
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@nl
prefLabel
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@ast
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@en
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@nl
P2093
P2860
P356
P1476
Regioselective arene halogenation using the FAD-dependent halogenase RebH.
@en
P2093
James T Payne
Jared C Lewis
Mary C Andorfer
P2860
P304
P356
10.1002/ANIE.201300762
P407
P577
2013-04-16T00:00:00Z