Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF - Wikidata - wikimedia - TriplyDB

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

http://www.wikidata.org/entity/Q34339833

about

Gene-based therapy of Parkinson's Disease: Translation from animal model to human clinical trial employing convection enhanced delivery GDNF-transfected macrophages produce potent neuroprotective effects in Parkinson's disease mouse model A monoclonal antibody-GDNF fusion protein is not neuroprotective and is associated with proliferative pancreatic lesions in parkinsonian monkeys Intraoperative intracerebral MRI-guided navigation for accurate targeting in nonhuman primates Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target.Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys Convection Enhanced Delivery: A Comparison of infusion characteristics in ex vivo and in vivo non-human primate brain tissue Titer and product affect the distribution of gene expression after intraputaminal convection-enhanced delivery.An adeno-associated virus-based intracellular sensor of pathological nuclear factor-κB activation for disease-inducible gene transfer.Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain.Aged monkeys as a partial model for Parkinson's disease.The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys.Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model.Efficient Expression of Igf-1 from Lentiviral Vectors Protects In Vitro but Does Not Mediate Behavioral Recovery of a Parkinsonian Lesion in Rats.Induced pluripotent stem cell-derived neural cells survive and mature in the nonhuman primate brain.Pathways of infusate loss during convection-enhanced delivery into the putamen nucleus Intracerebral transplantation of differentiated human embryonic stem cells to hemiparkinsonian monkeys.Neuroprotective Properties of a Novel Non-Thiazoledinedione Partial PPAR- γ Agonist against MPTP.Impact of age and vector construct on striatal and nigral transgene expression.Coexpression of recombinant adenovirus carrying GDNF and EDNRB genes in neural stem cells in vitro.Neuroprotective Surgical Strategies in Parkinson's Disease: Role of Preclinical Data.Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease.

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P2860

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

http://www.wikidata.org/entity/Q34339833

description

2009 nî lūn-bûn

@nan

2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2009 թվականի օգոստոսին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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name

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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type

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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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prefLabel

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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J.NBD.2009.07.022

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Neurobiology of Disease

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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

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A D Ebert

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B Roitberg

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J E Holden

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M E Emborg

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P Aebischer

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P2860

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

Alzheimer Disease in the US Population

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

Menopause in nonhuman primates?

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

Crossroads in GDNF therapy for Parkinson's disease

Chronic Parkinsonism secondary to intravenous injection of meperidine analogues

Oral levodopa dose-response study in MPTP-induced hemiparkinsonian monkeys: assessment with a new rating scale for monkey parkinsonism

Parkinson's disease: mechanisms and models

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

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