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Receptor agonists of macrophage migration inhibitory factor.

Receptor agonists of macrophage migration inhibitory factor.

http://www.wikidata.org/entity/Q34340164

about

A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF)Structural Interactions Dictate the Kinetics of Macrophage Migration Inhibitory Factor Inhibition by Different Cancer-Preventive Isothiocyanates Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment Role of macrophage migration inhibitory factor in age-related lung disease Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis.MIF, a controversial cytokine: a review of structural features, challenges, and opportunities for drug development.A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine lung.Benzisothiazolones as modulators of macrophage migration inhibitory factor.Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor.Biomolecular Force Field Parameterization via Atoms-in-Molecule Electron Density Partitioning An Analysis of MIF Structural Features that Control Functional Activation of CD74.Homotrimeric macrophage migration inhibitory factor (MIF) drives inflammatory responses in the corneal epithelium by promoting caveolin-rich platform assembly in response to infection.Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasia.Characterization of biaryl torsional energetics and its treatment in OPLS all-atom force fields AMPK Activators as a Drug for Diabetes, Cancer and Cardiovascular Disease Limiting cardiac ischemic injury by pharmacological augmentation of macrophage migration inhibitory factor-AMP-activated protein kinase signal transduction.Macrophage migration inhibitory factor deficiency augments doxorubicin-induced cardiomyopathy.MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis.Brain miffed by macrophage migration inhibitory factor.Macrophage Migration Inhibitory Factor Limits Renal Inflammation and Fibrosis by Counteracting Tubular Cell Cycle Arrest.Dysregulated D-dopachrome tautomerase, a hypoxia-inducible factor-dependent gene, cooperates with macrophage migration inhibitory factor in renal tumorigenesis.MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics.Virtual screening and optimization yield low-nanomolar inhibitors of the tautomerase activity of Plasmodium falciparum macrophage migration inhibitory factor.

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P2860

Receptor agonists of macrophage migration inhibitory factor.

http://www.wikidata.org/entity/Q34340164

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Receptor agonists of macrophage migration inhibitory factor.

@ast

Receptor agonists of macrophage migration inhibitory factor.

@en

Receptor agonists of macrophage migration inhibitory factor.

@nl

type

label

Receptor agonists of macrophage migration inhibitory factor.

@ast

Receptor agonists of macrophage migration inhibitory factor.

@en

Receptor agonists of macrophage migration inhibitory factor.

@nl

prefLabel

Receptor agonists of macrophage migration inhibitory factor.

@ast

Receptor agonists of macrophage migration inhibitory factor.

@en

Receptor agonists of macrophage migration inhibitory factor.

@nl

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J.BMCL.2010.09.118

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Bioorganic & Medicinal Chemistry Letters

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Receptor agonists of macrophage migration inhibitory factor.

@en

P2093

Alexander Trofimov

http://www.w3.org/2001/XMLSchema#string

Alissa A Hare

http://www.w3.org/2001/XMLSchema#string

Lin Leng

http://www.w3.org/2001/XMLSchema#string

Sunilkumar Gandavadi

http://www.w3.org/2001/XMLSchema#string

Xin Du

http://www.w3.org/2001/XMLSchema#string

P2860

MIF signal transduction initiated by binding to CD74

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex

Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity

Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants

The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents

Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site

Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.

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7033-7036

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10.1016/J.BMCL.2010.09.118

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William L. Jorgensen

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2010-09-29T00:00:00Z

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