DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis - Wikidata - wikimedia - TriplyDB

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

http://www.wikidata.org/entity/Q34340260

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Towards tumor immunodiagnostics Roles for retrotransposon insertions in human disease Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity Managing Single-Stranded DNA during Replication Stress in Fission Yeast Breaking bad: The mutagenic effect of DNA repair Mutational signatures: the patterns of somatic mutations hidden in cancer genomes Emerging patterns of somatic mutations in cancer Activation-induced deoxycytidine deaminase (AID) co-transcriptional scanning at single-molecule resolution.APOBEC3 Interference during Replication of Viral Genomes AID/APOBEC deaminases and cancer Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer Hypermutation in human cancer genomes: footprints and mechanisms APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication Michael S. Neuberger 1953-2013 Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase Interaction of APOBEC3A with DNA assessed by atomic force microscopy Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer Signatures of mutational processes in human cancer Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.Is homologous recombination really an error-free process?Induction of homologous recombination between sequence repeats by the activation induced cytidine deaminase (AID) protein Expression profiling of genes modulated by minocycline in a rat model of neuropathic pain Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.Diverse modes of genomic alteration in hepatocellular carcinoma C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency Repair of naturally occurring mismatches can induce mutations in flanking DNA.Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis.Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers Vif Proteins from Diverse Human Immunodeficiency Virus/Simian Immunodeficiency Virus Lineages Have Distinct Binding Sites in A3C.B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.Break-induced replication is a source of mutation clusters underlying kataegis Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death.APOBEC3A functions as a restriction factor of human papillomavirus Engineered proteins detect spontaneous DNA breakage in human and bacterial cells.

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P2860

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

http://www.wikidata.org/entity/Q34340260

description

2013 nî lūn-bûn

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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի ապրիլին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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DNA deaminases induce break-as ...... d 3A in breast cancer kataegis

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Benjamin Jm Taylor

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Cristina Rada

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Lucy A Stebbings

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Michael S Neuberger

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Peter J Campbell

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Yee Ling Wu

http://www.w3.org/2001/XMLSchema#string

P2860

AID/APOBEC cytosine deaminase induces genome-wide kataegis

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

Mutational processes molding the genomes of 21 breast cancers

Fast and accurate short read alignment with Burrows-Wheeler transform

Deoxycytidyl transferase activity of yeast REV1 protein.

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

Multifunctional yeast high-copy-number shuttle vectors

Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

Genome instability: a mechanistic view of its causes and consequences

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scholarly article

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10.7554/ELIFE.00534

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2

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Serena Nik-Zainal

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