Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia - Wikidata - wikimedia - TriplyDB

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia

http://www.wikidata.org/entity/Q34340579

about

Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions The response-to-retention hypothesis of early atherogenesis Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine Genomic organization and regulation of expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) gene Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man Probucol attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin Unique repetitive sequence and unexpected regulation of expression of rat endothelial receptor for oxidized low-density lipoprotein (LOX-1)Cholesteryl ester accumulation in macrophages incubated with low density lipoprotein pretreated with cigarette smoke extract Low density lipoprotein rich in oleic acid is protected against oxidative modification: implications for dietary prevention of atherosclerosis Why are low-density lipoproteins atherogenic?Atherosclerosis: inhibition of regression as therapeutic possibilities Oxidised low density lipoproteins and atherogenesis.Role of oxidised low density lipoprotein in atherogenesis Modification of atherosclerosis by agents that do not lower cholesterol The role of oxidative stress in atherosclerosis: the hope and the hype d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties.Antioxidant defenses and lipid peroxidation in human blood plasma.Oxidized low density lipoprotein: atherogenic and proinflammatory characteristics during macrophage foam cell formation. An inhibitory role for nutritional antioxidants and serum paraoxonase.Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein Dissociation of atherogenesis from aortic accumulation of lipid hydro(pero)xides in Watanabe heritable hyperlipidemic rabbits.Anion-exchange HPLC separation of five major rabbit lipoproteins using a nonporous diethylaminoethyl-ligated gel with a perchlorate-containing eluent.Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate.Intact human ceruloplasmin oxidatively modifies low density lipoprotein.Antioxidant: a new role for RU-486 and related compounds Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. I. Is the extent of atherosclerosis related to resistance of LDL to oxidation?A comparison of the antiatherogenic effects of probucol and of a structural analogue of probucol in low density lipoprotein receptor-deficient rabbits.Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions Preservation of the endogenous antioxidants in low density lipoprotein by ascorbate but not probucol during oxidative modification Minimally modified low density lipoprotein stimulates monocyte endothelial interactions.Minimally modified low density lipoprotein is biologically active in vivo in mice.Cardiovascular disease and nutrient antioxidants: role of low-density lipoprotein oxidation.Effects of ACE inhibitors on oxidation of human low density lipoprotein Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atheroscleros Effect of antioxidants on oxidative modification of LDL.Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse Recognition of oxidatively damaged erythrocytes by a macrophage receptor with specificity for oxidized low density lipoprotein.

P2860

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P2860

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia

http://www.wikidata.org/entity/Q34340579

description

1987 nî lūn-bûn

@nan

1987 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1987 թվականի օգոստոսին հրատարակված գիտական հոդված

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1987年の論文

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1987年学术文章

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1987年学术文章

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1987年学术文章

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1987年学术文章

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1987年学术文章

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1987年學術文章

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name

Probucol prevents the progress ...... familial hypercholesterolemia

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Probucol prevents the progress ...... familial hypercholesterolemia

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Probucol prevents the progress ...... familial hypercholesterolemia

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type

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Probucol prevents the progress ...... familial hypercholesterolemia

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Probucol prevents the progress ...... familial hypercholesterolemia

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Probucol prevents the progress ...... familial hypercholesterolemia

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prefLabel

Probucol prevents the progress ...... familial hypercholesterolemia

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Probucol prevents the progress ...... familial hypercholesterolemia

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Probucol prevents the progress ...... familial hypercholesterolemia

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PNAS.84.16.5928

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Proceedings of the National Academy of Sciences of the United States of America

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Probucol prevents the progress ...... familial hypercholesterolemia

@en

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Ishii K

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Kawai C

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Kita T

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Kume N

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Ooshima A

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Yokode M

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P2860

Protein measurement with the Folin phenol reagent

Liver transplantation to provide low-density-lipoprotein receptors and lower plasma cholesterol in a child with homozygous familial hypercholesterolemia

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor

A receptor-mediated pathway for cholesterol homeostasis

Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins

Probucol inhibits oxidative modification of low density lipoprotein.

Cellular pathology of homozygous familial hypercholesterolemia.

Stimulation of cholesteryl ester synthesis in mouse peritoneal macrophages by cholesterol-rich very low density lipoproteins from the Watanabe heritable hyperlipidemic rabbit, an animal model of familial hypercholesterolemia.

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

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5928-5931

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scholarly article

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10.1073/PNAS.84.16.5928

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16

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84

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19680050

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3475709

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atherosclerosis

hypercholesterolemia

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298976

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