The roles and mechanisms of PAR4 and P2Y12/phosphatidylinositol 3-kinase pathway in maintaining thrombin-induced platelet aggregation
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Thrombin and vascular inflammationHPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases.Protease-activated receptors in cancer: A systematic review.The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic ActivityChlorin e6 Prevents ADP-Induced Platelet Aggregation by Decreasing PI3K-Akt Phosphorylation and Promoting cAMP Production.Highly electronegative LDL from patients with ST-elevation myocardial infarction triggers platelet activation and aggregationProtease-activated receptor 4: from structure to function and back again.Functional, Cellular, and Molecular Remodeling of the Heart under Influence of Oxidative Cigarette Tobacco Smoke.Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4).Antiplatelet and antithrombotic effect of F 16618, a new thrombin proteinase-activated receptor-1 (PAR1) antagonist.PKC inhibition markedly enhances Ca2+ signaling and phosphatidylserine exposure downstream of protease-activated receptor-1 but not protease-activated receptor-4 in human platelets.A critical role of thrombin/PAR-1 in ADP-induced platelet secretion and the second wave of aggregation.Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleeding.PAR4 (Protease-Activated Receptor 4) Antagonism With BMS-986120 Inhibits Human Ex Vivo Thrombus Formation.Evaluation of the tolerability and immunogenicity of ultraviolet C-irradiated autologous platelets in a dog model.Dual inhibition of PI3K and mTOR by VS-5584 suppresses thrombus formation.Role of P2Y12 Receptor in Thrombosis.Inhibition of protease-activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood.
P2860
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P2860
The roles and mechanisms of PAR4 and P2Y12/phosphatidylinositol 3-kinase pathway in maintaining thrombin-induced platelet aggregation
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The roles and mechanisms of PA ...... n-induced platelet aggregation
@ast
The roles and mechanisms of PA ...... n-induced platelet aggregation
@en
The roles and mechanisms of PA ...... n-induced platelet aggregation
@nl
type
label
The roles and mechanisms of PA ...... n-induced platelet aggregation
@ast
The roles and mechanisms of PA ...... n-induced platelet aggregation
@en
The roles and mechanisms of PA ...... n-induced platelet aggregation
@nl
prefLabel
The roles and mechanisms of PA ...... n-induced platelet aggregation
@ast
The roles and mechanisms of PA ...... n-induced platelet aggregation
@en
The roles and mechanisms of PA ...... n-induced platelet aggregation
@nl
P2093
P2860
P1476
The roles and mechanisms of PA ...... n-induced platelet aggregation
@en
P2093
Che-Ming Teng
Chieh-Yu Liao
Chin-Chung Wu
Sheng-Chu Kuo
Shih-Yun Wu
Yang-Chang Wu
P2860
P304
P356
10.1111/J.1476-5381.2010.00921.X
P407
P577
2010-10-01T00:00:00Z