Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
about
MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNAThe effect of the 2-amino group of 7,8-dihydro-8-oxo-2'-deoxyguanosine on translesion synthesis and duplex stabilitySequence determination of nucleic acids containing 5-methylisocytosine and isoguanine: identification and insight into polymerase replication of the non-natural nucleobasesStepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.Base excision repair and cancerThe structural basis for the mutagenicity of O6-methyl-guanine lesionsHydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4Impact of Conformational Heterogeneity of OxoG Lesions and Their Pairing Partners on Bypass Fidelity by Y Family PolymerasesStructure of Human DNA Polymerase κ Inserting dATP Opposite an 8-OxoG DNA LesionStructural and Functional Elucidation of the Mechanism Promoting Error-prone Synthesis by Human DNA Polymerase Opposite the 7,8-Dihydro-8-oxo-2'-deoxyguanosine AdductMolecular Basis of Transcriptional Mutagenesis at 8-OxoguanineEncounter and extrusion of an intrahelical lesion by a DNA repair enzymeThe Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation AnalysisCrystal Structure of a Replicative DNA Polymerase Bound to the Oxidized Guanine Lesion Guanidinohydantoin ,Replication through an abasic DNA lesion: structural basis for adenine selectivitySubstitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP To Be Inserted opposite 7,8-Dihydro-8-oxoguanine,Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active siteChemical discrimination between dC and 5MedC via their hydroxylamine adductsStructural Basis for Error-free Replication of Oxidatively Damaged DNA by Yeast DNA Polymerase ηUnique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iotaIn Vivo, in Vitro, and X-ray Crystallographic Analyses Suggest the Involvement of an Uncharacterized Triose-phosphate Isomerase (TIM) Barrel Protein in Protection against Oxidative StressThe Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active SiteDNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesionBinary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesionStructural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and RibonucleotidesUnexpected non-Hoogsteen-based mutagenicity mechanism of FaPy-DNA lesionsN7 methylation alters hydrogen-bonding patterns of guanine in duplex DNAReactive Oxygen Species Play an Important Role in the Bactericidal Activity of Quinolone AntibioticsA fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dGThe 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae.A switch between DNA polymerases δ and λ promotes error-free bypass of 8-oxo-G lesionsDNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primersA nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycolA transposon-derived DNA polymerase from Entamoeba histolytica displays intrinsic strand displacement, processivity and lesion bypassBase-excision repair of oxidative DNA damageParkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundanceDistinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides.Variations on a theme: eukaryotic Y-family DNA polymerasesCapturing a mammalian DNA polymerase extending from an oxidized nucleotide.Direct detection of DNA methylation during single-molecule, real-time sequencing.
P2860
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P2860
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
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name
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@ast
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@en
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@nl
type
label
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@ast
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@en
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@nl
prefLabel
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@ast
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@en
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@nl
P2093
P2860
P356
P1433
P1476
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
@en
P2093
Gerald W Hsu
Lorena S Beese
Matthias Ober
P2860
P2888
P304
P356
10.1038/NATURE02908
P407
P577
2004-08-22T00:00:00Z
P5875
P6179
1030447477