Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines.
about
Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomesAcute effects of the sigma-2 receptor agonist siramesine on lysosomal and extra-lysosomal proteolytic systems in lens epithelial cells.Identification of the gene that codes for the σ2 receptor.Characterization of interactions of 4-nitrophenylpropyl-N-alkylamine with ς receptors.Lysosomal membrane permeabilization is an early event in Sigma-2 receptor ligand mediated cell death in pancreatic cancer.Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer.Synthesis and in vitro evaluation of tetrahydroisoquinolinyl benzamides as ligands for sigma receptorsPET radiotracers for imaging P-glycoprotein: the challenge for early diagnosis in AD.Possible biomarkers modulating haloperidol efficacy and/or tolerability.Targeting Nanocarriers with Anisamide: Fact or Artifact?Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: hints for collateral sensitivity.2-Aminopyridine derivatives as potential σ(2) receptor antagonists.Sigma1 Pharmacology in the Context of Cancer.1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity.Multi-drug-resistance-reverting agents: 2-aryloxazole and 2-arylthiazole derivatives as potent BCRP or MRP1 inhibitors.Altered expression level of Sigma1 receptor gene in human colorectal cancer.Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress.Multifunctional thiosemicarbazones and deconstructed analogues as a strategy to study the involvement of metal chelation, Sigma-2 (σ2) receptor and P-gp protein in the cytotoxic action: In vitro and in vivo activity in pancreatic tumors.Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma.Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.Design, synthesis, lipophilic properties, and binding affinities of potential ligands in positron emission tomography (PET) for visualization of brain dopamine D4 receptors.
P2860
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P2860
Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
name
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@ast
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@en
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@nl
type
label
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@ast
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@en
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@nl
prefLabel
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@ast
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@en
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@nl
P2093
P50
P1476
Antiproliferative and cytotoxi ...... agonists in tumour cell lines.
@en
P2093
Francesco Berardi
Nicola Antonio Colabufo
Roberto Perrone
Vincenzo Tortorella
P2888
P304
P356
10.1007/S00210-004-0961-2
P577
2004-07-31T00:00:00Z
P6179
1036968899