Polytriazoles as copper(I)-stabilizing ligands in catalysis.
about
Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cellsLabeling live cells by copper-catalyzed alkyne--azide click chemistryBioorthogonal chemistry: fishing for selectivity in a sea of functionalityCopper-free click chemistry for dynamic in vivo imagingClick chemistry in complex mixtures: bioorthogonal bioconjugationBioorthogonal chemistry: strategies and recent developmentsStructure-Based Development of an Affinity Probe for Sirtuin 2Development and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal ReactionModular and orthogonal synthesis of hybrid polymers and networksMesofluidic devices for DNA-programmed combinatorial chemistryDiscovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate libraryScalable C-H Oxidation with Copper: Synthesis of PolyoxypregnanesCombination probes with intercalating anchors and proximal fluorophores for DNA and RNA detectionSite-specific protein labeling using PRIME and chelation-assisted click chemistryImaging the glycome in living systemsSite-specific bioconjugation of a murine dihydrofolate reductase enzyme by copper(I)-catalyzed azide-alkyne cycloaddition with retained activitySite-specific fatty acid-conjugation to prolong protein half-life in vivoSuper-resolution optical DNA Mapping via DNA methyltransferase-directed click chemistry.Two-dimensional combinatorial screening identifies specific 6'-acylated kanamycin A- and 6'-acylated neamine-RNA hairpin interactions.Scaffold optimization in discontinuous epitope containing protein mimics of gp120 using smart libraries.Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acidsUse of click chemistry to define the substrate specificity of Leishmania beta-1,2-mannosyltransferases.A two stage click-based library of protein tyrosine phosphatase inhibitorsConformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues.Small molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group I intronA tris(triazolate) ligand for a highly active and magnetically recoverable palladium catalyst of selective alcohol oxidation using air at atmospheric pressure.Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efficiently identify aminoglycoside-RNA hairpin loop interactionsNucleoside triphosphate mimicry: a sugar triazolyl nucleoside as an ATP-competitive inhibitor of B. anthracis pantothenate kinase.Colorimetric Cu(2+) detection using DNA-modified gold-nanoparticle aggregates as probes and click chemistry.Two-dimensional combinatorial screening of a bacterial rRNA A-site-like motif library: defining privileged asymmetric internal loops that bind aminoglycosides.Synthesis of an azide-tagged library of 2,3-dihydro-4-quinolones.Selective gamma-ketoaldehyde scavengers protect Nav1.5 from oxidant-induced inactivation.2-Dialkynyl derivatives of (N)-methanocarba nucleosides: 'Clickable' A(3) adenosine receptor-selective agonists.Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitorA microarray-based method to perform nucleic acid selections.Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe.Glycans in pathogenic bacteria--potential for targeted covalent therapeutics and imaging agents.Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes.
P2860
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P2860
Polytriazoles as copper(I)-stabilizing ligands in catalysis.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Polytriazoles as copper
@nl
Polytriazoles as copper(I)-stabilizing ligands in catalysis.
@ast
Polytriazoles as copper(I)-stabilizing ligands in catalysis.
@en
type
label
Polytriazoles as copper
@nl
Polytriazoles as copper(I)-stabilizing ligands in catalysis.
@ast
Polytriazoles as copper(I)-stabilizing ligands in catalysis.
@en
prefLabel
Polytriazoles as copper
@nl
Polytriazoles as copper(I)-stabilizing ligands in catalysis.
@ast
Polytriazoles as copper(I)-stabilizing ligands in catalysis.
@en
P356
P1433
P1476
Polytriazoles as copper(I)-stabilizing ligands in catalysis.
@en
P2093
Robert Hilgraf
Timothy R Chan
P304
P356
10.1021/OL0493094
P407
P577
2004-08-01T00:00:00Z