Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.

Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.

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http://www.wikidata.org/entity/Q34344454
Plasminogen kringle 5 induces endothelial cell apoptosis by triggering a voltage-dependent anion channel 1 (VDAC1) positive feedback loopCancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 productionCell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP.EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity.Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.LRP-1 promotes cancer cell invasion by supporting ERK and inhibiting JNK signaling pathwaysModification of cyclic NGR tumor neovasculature-homing motif sequence to human plasminogen kringle 5 improves inhibition of tumor growth.Dual inhibition of plasminogen kringle 5 on angiogenesis and chemotaxis suppresses tumor metastasis by targeting HIF-1α pathway.The critical role of GRP78 in physiologic and pathologic stress.A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasisGRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach.Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targetingTargeting GRP78 and antiestrogen resistance in breast cancer.Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potentialCombination of pigment epithelium-derived factor with radiotherapy enhances the antitumor effects on nasopharyngeal carcinoma by downregulating vascular endothelial growth factor expression and angiogenesis.Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma.Plasminogen kringle 5 suppresses gastric cancer via regulating HIF-1α and GRP78.
P2860

Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.

Item
http://www.wikidata.org/entity/Q34344454
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@ast
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@en
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@nl
type
label
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@ast
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@en
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@nl
prefLabel
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@ast
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@en
Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
@nl
P1433
P1476
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P31
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P698
P921
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P1433
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Plasminogen kringle 5 induces ...... equirement for GRP78 and LRP1.
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P2093
P2860
P304
P31
P356
10.1158/0008-5472.CAN-08-4841
P407
P433
P478
P577
P698
P921
P932