Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome. - Wikidata - wikimedia - TriplyDB

Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome.

Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome.

http://www.wikidata.org/entity/Q34344688

about

Mechanisms of Aβ Clearance and Degradation by Glial Cells New mechanisms of metformin action: Focusing on mitochondria and the gut Clearance systems in the brain-implications for Alzheimer disease NLRP3 inflammasome and its inhibitors: a review Autophagosome dynamics in neurodegeneration at a glance NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease.Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.miR-Let7A Modulates Autophagy Induction in LPS-Activated Microglia Calpain-mediated cleavage of DARPP-32 in Alzheimer's disease.Activation of Cannabinoid Receptor 2 Ameliorates DSS-Induced Colitis through Inhibiting NLRP3 Inflammasome in Macrophages.Caloric restriction reduces the systemic progression of mouse AApoAII amyloidosis.Optineurin: The autophagy connection.Resveratrol Enhances Autophagic Flux and Promotes Ox-LDL Degradation in HUVECs via Upregulation of SIRT1 AIM 2 inflammasomes regulate neuronal morphology and influence anxiety and memory in mice Autophagy resolves early retinal inflammation in Igf1-deficient mice Regulation of amyloid precursor protein processing by its KFERQ motif.Impaired macrophage autophagy induces systemic insulin resistance in obesity Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging.Atorvastatin ameliorates LPS-induced inflammatory response by autophagy via AKT/mTOR signaling pathway.Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology.The fine-tuning of proteolytic pathways in Alzheimer's disease.Glial alterations from early to late stages in a model of Alzheimer's disease: Evidence of autophagy involvement in Aβ internalization.Autophagy and Alzheimer's Disease.The burgeoning field of innate immune-mediated disease and autoinflammation.Autophagy regulates MAVS signaling activation in a phosphorylation-dependent manner in microglia.The protective effect of Epimedii Folium and Curculiginis Rhizoma on Alzheimer's disease by the inhibitions of NF-κB/MAPK pathway and NLRP3 inflammasome.Microglia-Synapse Pathways: Promising Therapeutic Strategy for Alzheimer's Disease.Deficient autophagy in microglia impairs synaptic pruning and causes social behavioral defects TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.Inflammasomes in neurological diseases: emerging pathogenic and therapeutic concepts.Orexin Impairs the Phagocytosis and Degradation of Amyloid-β Fibrils by Microglial Cells.Activating α7 nicotinic acetylcholine receptor inhibits NLRP3 inflammasome through regulation of β-arrestin-1.RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.MicroRNA-214-3p: A link between autophagy and endothelial cell dysfunction in atherosclerosis.Autophagy impairment by caspase-1-dependent inflammation mediates memory loss in response to β-Amyloid peptide accumulation.Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model.Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice.Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7.Microglial Phagocytosis and Its Regulation: A Therapeutic Target in Parkinson's Disease?

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P2860

Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome.

http://www.wikidata.org/entity/Q34344688

description

2014 nî lūn-bûn

@nan

2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@ast

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@en

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@nl

type

label

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@ast

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@en

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@nl

prefLabel

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@ast

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@en

Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@nl

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Autophagy in microglia degrade ...... ulates the NLRP3 inflammasome.

@en

P2093

Dong-Hou Kim

http://www.w3.org/2001/XMLSchema#string

Eun-Young Jeon

http://www.w3.org/2001/XMLSchema#string

Hoe-Jin Kang

http://www.w3.org/2001/XMLSchema#string

Hong-Mi Kim

http://www.w3.org/2001/XMLSchema#string

Hun-Sik Kim

http://www.w3.org/2001/XMLSchema#string

Hyung-Joon Kwon

http://www.w3.org/2001/XMLSchema#string

Kwangmin Cho

http://www.w3.org/2001/XMLSchema#string

Mi-Hyang Cho

http://www.w3.org/2001/XMLSchema#string

Seung-Yong Yoon

http://www.w3.org/2001/XMLSchema#string

P2860

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

The inflammasomes

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

Autophagy in immunity and inflammation

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells

Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin

Microglia and neuroinflammation: a pathological perspective

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.

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1761-1775

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scholarly article

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10.4161/AUTO.29647

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10

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10

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25126727

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4198361

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