Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes.
about
The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reductionAnticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanatesPolyphenols as Modulator of Oxidative Stress in Cancer Disease: New Therapeutic StrategiesSmall molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agentsInteraction of sulforaphane with DNA and RNAChemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moietyLAS0811: from combinatorial chemistry to activation of antioxidant response element.Electrophilic tuning of the chemoprotective natural product sulforaphane.An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1Dietary regulation of histone acetylases and deacetylases for the prevention of metabolic diseases.Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2.Effect of indole ethyl isothiocyanates on proliferation, apoptosis, and MAPK signaling in neuroblastoma cell linesDiscovery and development of sulforaphane as a cancer chemopreventive phytochemical.Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential.Preparation of Disubstituted Phenyl Propargyl Alcohols, their Use in Oxathiolene Oxide Synthesis, and Evaluation of the Oxathiolene Oxide Products as Anticarcinogenic Enzyme Inducers.The cytoprotective role of the Keap1-Nrf2 pathway.A fascination with enzymes: the journey not the arrival matters.Sulforaphane Induces Cell Death Through G2/M Phase Arrest and Triggers Apoptosis in HCT 116 Human Colon Cancer Cells.Selenium as a chemopreventive agent in experimentally induced colon carcinogenesisRole of dietary supplements/nutraceuticals in chemoprevention through induction of cytoprotective enzymes.DNA damage-mediated apoptosis induced by selenium compounds.Immunotoxicity of zearalenone in Balb/c mice in a high subchronic dosing study counteracted by Raphanus sativus extract.Design, Synthesis, and Evaluation of ω-(Isothiocyanato)alkylphosphinates and Phosphine Oxides as Antiproliferative Agents.HPLC-based kinetics assay facilitates analysis of systems with multiple reaction products and thermal enzyme denaturation.Cognition Enhancing Activity of Sulforaphane Against Scopolamine Induced Cognitive Impairment in Zebra Fish (Danio rerio).Inhibition of oxidative DNA damage in vitro by extracts of brussels sprouts.Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast.Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells.
P2860
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P2860
Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@ast
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@en
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@nl
type
label
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@ast
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@en
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@nl
prefLabel
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@ast
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@en
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@nl
P2093
P356
P1476
Design and synthesis of bifunc ...... inogenic detoxication enzymes.
@en
P2093
P304
P356
10.1021/JM00027A021
P407
P577
1994-01-01T00:00:00Z