Interaction of novel hybrid compounds with the D3 dopamine receptor: Site-directed mutagenesis and homology modeling studies

Interaction of novel hybrid compounds with the D3 dopamine receptor: Site-directed mutagenesis and homology modeling studies

Item
http://www.wikidata.org/entity/Q34348803
Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluationNovel bivalent ligands for D2/D3 dopamine receptors: Significant co-operative gain in D2 affinity and potency.Efficacy of Hybrid Tetrahydrobenzo[d]thiazole Based Aryl Piperazines D-264 and D-301 at D₂ and D₃ ReceptorsModification of agonist binding moiety in hybrid derivative 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-1-ol/-2-amino versions: impact on functional activity and selectivity for dopamine D2/D3 receptorsStructural modifications of neuroprotective anti-Parkinsonian (-)-N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (D-264): an effort toward the improvement of in vivo efficacy of the parent molInsights into the structural biology of G-protein coupled receptors impacts drug design for central nervous system neurodegenerative processes.Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds.Identification and characterization of a novel class of atypical dopamine receptor agonists.A Molecular Basis for Selective Antagonist Destabilization of Dopamine D3 Receptor Quaternary Organization.Functional reversal of (-)-Stepholidine analogues by replacement of benzazepine substructure using the ring-expansion strategy.Current therapeutic molecules and targets in neurodegenerative diseases based on in silico drug design.
P2860

Interaction of novel hybrid compounds with the D3 dopamine receptor: Site-directed mutagenesis and homology modeling studies

Item
http://www.wikidata.org/entity/Q34348803
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Interaction of novel hybrid co ...... and homology modeling studies
@ast
Interaction of novel hybrid co ...... and homology modeling studies
@en
Interaction of novel hybrid co ...... and homology modeling studies
@nl
type
label
Interaction of novel hybrid co ...... and homology modeling studies
@ast
Interaction of novel hybrid co ...... and homology modeling studies
@en
Interaction of novel hybrid co ...... and homology modeling studies
@nl
prefLabel
Interaction of novel hybrid co ...... and homology modeling studies
@ast
Interaction of novel hybrid co ...... and homology modeling studies
@en
Interaction of novel hybrid co ...... and homology modeling studies
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Interaction of novel hybrid co ...... and homology modeling studies
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P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932