Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. - Wikidata - wikimedia - TriplyDB

Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.

Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.

http://www.wikidata.org/entity/Q34351124

about

Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase Physiological and pathological implications of 5-hydroxymethylcytosine in diseases IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma Regulation of the Epigenome by Vitamin C Developing epigenetic diagnostics and therapeutics for brain disorders Epigenetics and the developmental origins of inflammatory bowel diseases 2-Hydoxyglutarate: D/Riving Pathology in gLiomaS Prostate cancer epigenetics and its clinical implications Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis 5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients.Hydroxymethylation as a Novel Environmental Biosensor High expression of 5-hydroxymethylcytosine and isocitrate dehydrogenase 2 is associated with favorable prognosis after curative resection of hepatocellular carcinoma.Potential serum biomarkers for glioblastoma diagnostic assessed by proteomic approaches.Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma Chromatin Memory in the Development of Human Cancers 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies Clinical significance of DNA methylation mRNA levels of TET family members in colorectal cancer.Global 5-Hydroxymethylcytosine Levels Are Profoundly Reduced in Multiple Genitourinary Malignancies IDH1R132H in Neural Stem Cells: Differentiation Impaired by Increased Apoptosis.Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis.5-hydroxymethylcytosine loss is associated with poor prognosis for patients with WHO grade II diffuse astrocytomas.Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis AF9 promotes hESC neural differentiation through recruiting TET2 to neurodevelopmental gene loci for methylcytosine hydroxylation.Epigenetics: a novel therapeutic approach for the treatment of Alzheimer's disease Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease.Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers.Alterations of 5-hydroxymethylcytosine in human cancers.Technical advances in global DNA methylation analysis in human cancers.Regulatory landscape and clinical implication of MBD3 in human malignant glioma.5-hydroxymethylcytosine: a new insight into epigenetics in cancer.5-hydroxymethylcytosine profiling as an indicator of cellular state.Recent advances in the bioanalysis of modified nucleotides in epigenetic studies.TET family proteins: new players in gliomas.The role of 5-hydroxymethylcytosine in human cancer.Oncometabolites-driven tumorigenesis: From genetics to targeted therapy.Circulating biomarker panels for targeted therapy in brain tumors.5-hydroxymethylcytosine: a potential therapeutic target in cancer.The application of genome-wide 5-hydroxymethylcytosine studies in cancer research.Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.

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Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma.

http://www.wikidata.org/entity/Q34351124

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

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Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

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Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

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type

label

Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

@ast

Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

@en

Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

@nl

prefLabel

Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

@ast

Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

@en

Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

@nl

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JOURNAL.PONE.0041036

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Decreased 5-hydroxymethylcytos ...... survival in malignant glioma.

@en

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Brent A Orr

http://www.w3.org/2001/XMLSchema#string

Michael C Haffner

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Srinivasan Yegnasubramanian

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William G Nelson

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P2860

Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA

DNA demethylation dynamics

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

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e41036

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scholarly article

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10.1371/JOURNAL.PONE.0041036

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7

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7

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Charles G Eberhart

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2012-07-19T00:00:00Z

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230566164

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22829908

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3400598

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