Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1. - Wikidata - wikimedia - TriplyDB

Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.

Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.

http://www.wikidata.org/entity/Q34353804

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Gene variants in CYP2C19 are associated with altered in vivo bupropion pharmacokinetics but not bupropion-assisted smoking cessation outcomes Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo Development and validation of a high-throughput stereoselective LC-MS/MS assay for bupropion, hydroxybupropion, erythrohydrobupropion, and threohydrobupropion in human plasma.Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS Carbonyl reduction pathways in drug metabolism.Stereoselective Metabolism of Bupropion to OH-bupropion, Threohydrobupropion, Erythrohydrobupropion, and 4'-OH-bupropion in vitro.Identification of non-reported bupropion metabolites in human plasma.Development, validation and application of a comprehensive stereoselective LC/MS-MS assay for bupropion and oxidative, reductive, and glucuronide metabolites in human urine.Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers.Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device.

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P2860

Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.

http://www.wikidata.org/entity/Q34353804

description

2013 nî lūn-bûn

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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2013 թվականի հունիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Formation of threohydrobupropi ...... ydroxysteroid dehydrogenase 1.

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Formation of threohydrobupropi ...... ydroxysteroid dehydrogenase 1.

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Formation of threohydrobupropi ...... ydroxysteroid dehydrogenase 1.

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Formation of threohydrobupropi ...... ydroxysteroid dehydrogenase 1.

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Formation of threohydrobupropi ...... ydroxysteroid dehydrogenase 1.

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Formation of threohydrobupropi ...... ydroxysteroid dehydrogenase 1.

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Formation of threohydrobupropi ...... ydroxysteroid dehydrogenase 1.

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Drug Metabolism and Disposition

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Formation of threohydrobupropi ...... ydroxysteroid dehydrogenase 1.

@en

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Agnieszka E Zielinska

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Alex Odermatt

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Anna Vuorinen

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Arne Meyer

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Gareth G Lavery

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Petra Strajhar

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P2860

Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase

The Protein Data Bank

15 years of clinical experience with bupropion HCl: from bupropion to bupropion SR to bupropion XL

Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes

Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D

Development and validation of a genetic algorithm for flexible docking

11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess

Improved protein-ligand docking using GOLD

Effect of ketoconazole on the pharmacokinetics of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor ABT-384 and its two active metabolites in healthy volunteers: population analysis of data from a drug-drug interaction study.

Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids

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1671-1678

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scholarly article

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10.1124/DMD.113.052936

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9

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41

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Daniela Schuster

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2013-06-26T00:00:00Z

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23804523

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3876805

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