Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis.
about
P1343
Type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) contributes to testosterone production in the adrenal reticularisRegulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factorPotential cellular conformations of the CCN3(NOV) proteinUpregulated JAG1 enhances cell proliferation in adrenocortical carcinomaSerine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndromeA unique co-culture model for fundamental and applied studies of human fetoplacental steroidogenesis and interference by environmental chemicalsRole of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cellsA role for the circadian clock protein Per1 in the regulation of aldosterone levels and renal Na+ retentionComputational model of steroidogenesis in human H295R cells to predict biochemical response to endocrine-active chemicals: model development for metyrapone.New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells.Two different cytochrome P450 enzymes are the adrenal antigens in autoimmune polyendocrine syndrome type I and Addison's diseaseHuman adrenocortical carcinoma cell lines.Comparison of aldosterone production among human adrenocortical cell lines.Human adrenal cells that express both 3β-hydroxysteroid dehydrogenase type 2 (HSD3B2) and cytochrome b5 (CYB5A) contribute to adrenal androstenedione production.Transcriptional regulation of the human P450 oxidoreductase gene: hormonal regulation and influence of promoter polymorphisms.NCI-H295R, a human adrenal cortex-derived cell line, expresses purinergic receptors linked to Ca²⁺-mobilization/influx and cortisol secretionDACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretionLGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human AdrenalAnimal models of adrenocortical tumorigenesisSteroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: implications for the mechanism of StAR action.Sunitinib Inhibits Cell Proliferation and Alters Steroidogenesis by Down-Regulation of HSD3B2 in Adrenocortical Carcinoma Cells.Fourth-Generation Progestins Inhibit 3β-Hydroxysteroid Dehydrogenase Type 2 and Modulate the Biosynthesis of Endogenous Steroids.Four clinically utilized drugs were identified and validated for treatment of adrenocortical cancer using quantitative high-throughput screeningPathways leading to phosphorylation of p450c17 and to the posttranslational regulation of androgen biosynthesisInhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis.Estimation of the Mechanism of Adrenal Action of Endocrine-Disrupting Compounds Using a Computational Model of Adrenal Steroidogenesis in NCI-H295R Cells.Regulation of aldosterone secretion by Cav1.3.The effects of the standardized extracts of Ginkgo biloba on steroidogenesis pathways and aromatase activity in H295R human adrenocortical carcinoma cells.Development of an adrenocorticotropin-responsive human adrenocortical carcinoma cell linePreclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma.Phosphorylation of human cytochrome P450c17 by p38α selectively increases 17,20 lyase activity and androgen biosynthesis.Estrogen biosynthesis in human H295 adrenocortical carcinoma cells.Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cellsEffect of insulin and testosterone on androgen production and transcription of SULT2A1 in the NCI-H295R adrenocortical cell line.Targeting heterogeneity of adrenocortical carcinoma: Evaluation and extension of preclinical tumor models to improve clinical translationCombined transcriptome and metabolome analyses of metformin effects reveal novel links between metabolic networks in steroidogenic systems.POD-1 binding to the E-box sequence inhibits SF-1 and StAR expression in human adrenocortical tumor cells.POD-1/TCF21 Reduces SHP Expression, Affecting LRH-1 Regulation and Cell Cycle Balance in Adrenocortical and Hepatocarcinoma Tumor Cells.Alternative splicing of DENND1A, a PCOS candidate gene, generates variant 2.Development of new preclinical models to advance adrenocortical carcinoma research.
P2860
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P2860
Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis.
description
1990 nî lūn-bûn
@nan
1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Establishment and characteriza ...... hways of steroid biosynthesis.
@ast
Establishment and characteriza ...... hways of steroid biosynthesis.
@en
Establishment and characteriza ...... hways of steroid biosynthesis.
@nl
type
label
Establishment and characteriza ...... hways of steroid biosynthesis.
@ast
Establishment and characteriza ...... hways of steroid biosynthesis.
@en
Establishment and characteriza ...... hways of steroid biosynthesis.
@nl
prefLabel
Establishment and characteriza ...... hways of steroid biosynthesis.
@ast
Establishment and characteriza ...... hways of steroid biosynthesis.
@en
Establishment and characteriza ...... hways of steroid biosynthesis.
@nl
P2093
P1433
P1476
Establishment and characteriza ...... hways of steroid biosynthesis.
@en
P2093
Brennan MF
Chrousos GP
La Rocca RV
Shackleton CH
P304
P407
P4510
P577
1990-09-01T00:00:00Z