Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi
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Glutamate-gated chloride channelsImmunization with L. sigmodontis microfilariae reduces peripheral microfilaraemia after challenge infection by inhibition of filarial embryogenesisA cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets WolbachiaProspects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseasesGlutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegansThe transcriptome analysis of Strongyloides stercoralis L3i larvae reveals targets for intervention in a neglected diseaseReproductive status of Onchocerca volvulus after ivermectin treatment in an ivermectin-naïve and a frequently treated population from CameroonThe Validation of Nematode-Specific Acetylcholine-Gated Chloride Channels as Potential Anthelmintic Drug TargetsThe Effects of Ivermectin on Brugia malayi Females In Vitro: A Transcriptomic ApproachIvermectin - Old Drug, New Tricks?Examining the role of macrolides and host immunity in combatting filarial parasites.How do the macrocyclic lactones kill filarial nematode larvae?High level expression of a glutamate-gated chloride channel gene in reproductive tissues of Brugia malayi may explain the sterilizing effect of ivermectin on filarial worms.A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasisIvermectin, 'wonder drug' from Japan: the human use perspective.Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics.Schistosome ABC multidrug transporters: From pharmacology to physiology.Utilization of computer processed high definition video imaging for measuring motility of microscopic nematode stages on a quantitative scale: "The Worminator".Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae.A histochemical study of the Nras/let-60 activity in filarial nematodes.Targeting Filarial Abl-like Kinases: Orally Available, Food and Drug Administration-Approved Tyrosine Kinase Inhibitors Are Microfilaricidal and Macrofilaricidal.Granulocytes in helminth infection -- who is calling the shots?Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivoSubunit stoichiometry and arrangement in a heteromeric glutamate-gated chloride channel.The Caenorhabditis elegans Excretory System: A Model for Tubulogenesis, Cell Fate Specification, and PlasticityGenotypic analysis of β-tubulin in Onchocerca volvulus from communities and individuals showing poor parasitological response to ivermectin treatment.Ion channels and receptor as targets for the control of parasitic nematodes.In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1.Progress and challenges in the discovery of macrofilaricidal drugs.The emergence of macrocyclic lactone resistance in the canine heartworm, Dirofilaria immitis.Molecular mechanisms for anthelmintic resistance in strongyle nematode parasites of veterinary importance.A Splendid Gift from the Earth: The Origins and Impact of the Avermectins (Nobel Lecture).Measuring the effect of avermectins and milbemycins on somatic muscle contraction of adult Haemonchus contortus and on motility of Ostertagia circumcincta in vitro.Ivermectin: enigmatic multifaceted 'wonder' drug continues to surprise and exceed expectations.Trapping of ivermectin by a pentameric ligand-gated ion channel upon open-to-closed isomerization.Development of an in vitro bioassay for measuring susceptibility to macrocyclic lactone anthelmintics in Dirofilaria immitisMutational Analysis at Intersubunit Interfaces of an Anionic Glutamate Receptor Reveals a Key Interaction Important for Channel Gating by Ivermectin.Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity.Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?Assessment of the safety and efficacy of three concentrations of topical ivermectin lotion as a treatment for head lice infestation.
P2860
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P2860
Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi
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2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
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2010年論文
@zh-mo
2010年論文
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2010年论文
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name
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@ast
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@en
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@nl
type
label
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@ast
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@en
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@nl
prefLabel
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@ast
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@en
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@nl
P2093
P2860
P356
P1476
Ivermectin disrupts the functi ...... microfilariae of Brugia malayi
@en
P2093
Charles D Mackenzie
Jonathan Solomon
Joseph F Nabhan
Timothy G Geary
Yovany Moreno
P2860
P304
20120-20125
P356
10.1073/PNAS.1011983107
P407
P577
2010-11-01T00:00:00Z