Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.
about
PI3K Signaling in Normal B Cells and Chronic Lymphocytic Leukemia (CLL)Idelalisib: First-in-Class PI3K Delta Inhibitor for the Treatment of Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, and Follicular LymphomaNo receptor stands alone: IgG B-cell receptor intrinsic and extrinsic mechanisms contribute to antibody memoryKidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.The cytoplasmic capping complex assembles on adapter protein nck1 bound to the proline-rich C-terminus of Mammalian capping enzymeCD19 controls Toll-like receptor 9 responses in human B cellsElucidation of tonic and activated B-cell receptor signaling in Burkitt's lymphoma provides insights into regulation of cell survivalXtalk: a path-based approach for identifying crosstalk between signaling pathwaysNcking BCR-mediated PI3K activation.Nck, a missing adaptor between the B-cell receptor complex and the BCAP/PI3K/Akt pathway.Does B cell receptor signaling in chronic lymphocytic leukaemia cells differ from that in other B cell types?CD40 signaling drives B lymphocytes into an intermediate memory-like state, poised between naïve and plasma cells.The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner.Cytoskeletal control of B cell responses to antigens.First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases.NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cellsLow Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.Conformational changes in the T cell receptor differentially determine T cell subset development in mice.Spin90 deficiency increases CXCL13-mediated B cell migration.Igβ ubiquitination activates PI3K signals required for endosomal sorting.Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation.A comparative global phosphoproteomics analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment.Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.Nck adaptor proteins modulate differentiation and effector function of T cells.Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells.
P2860
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P2860
Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Nck-mediated recruitment of BCAP to the BCR regulates the PI
@nl
Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.
@en
type
label
Nck-mediated recruitment of BCAP to the BCR regulates the PI
@nl
Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.
@en
prefLabel
Nck-mediated recruitment of BCAP to the BCR regulates the PI
@nl
Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.
@en
P2093
P2860
P356
P1433
P1476
Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.
@en
P2093
Angelo Castello
Anna Tafuri
Facundo D Batista
Johannes Tucholski
Jürgen Wienands
Kun-Hui Lu
Mauro Gaya
Michael Engelke
Thomas Oellerich
Tony Pawson
P2860
P304
P356
10.1038/NI.2685
P407
P577
2013-08-04T00:00:00Z